ArticleToxins2014
Toxins produced by Valsa mali var. mali and their relationship with pathogenicity.
Article in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
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- Preliminary Study of Main Pathogenicity Factors and Metabolites ofPlants (Basel, Switzerland) · 2026Article
- Identification, Subcellular Localization, and Infection-Related Expression of a Novel Haloacid Dehalogenase Gene (Journal of fungi (Basel, Switzerland) · 2025Article
- Identification and Biological Characteristics ofJournal of fungi (Basel, Switzerland) · 2024Article
- Uncovering the antifungal activities of wild apple-associated bacteria against two canker-causing fungi, Cytospora mali and C. parasitica.Scientific reports · 2024Article
- Xylanase VmXyl2 is involved in the pathogenicity ofFrontiers in plant science · 2024Article
- Transcription FactorJournal of fungi (Basel, Switzerland) · 2023Article
- Comparative genomics of five Valsa species gives insights on their pathogenicity evolution.G3 (Bethesda, Md.) · 2023Article
- A putative terpene cyclase gene (Frontiers in microbiology · 2023Article
- Identification of Structural Features of Hydrocinnamic Acid Related to Its Allelopathic Activity against the Parasitic WeedPlants (Basel, Switzerland) · 2022Article
- Biocontrol of strawberry gray mold caused byFrontiers in microbiology · 2022Article
- Hydroxybenzoate hydroxylase genes underlying protocatechuic acid production in Valsa mali are required for full pathogenicity in apple trees.Molecular plant pathology · 2021Article
- Nep1-like Proteins fromJournal of fungi (Basel, Switzerland) · 2021Article
- β-GlucosidaseFrontiers in microbiology · 2021Article
- LaeA Controls Virulence and Secondary Metabolism in Apple Canker PathogenFrontiers in microbiology · 2020Article
- MdUGT88F1-Mediated Phloridzin Biosynthesis Regulates Apple Development andPlant physiology · 2019Article
- Article
- Transcriptome analysis of Valsa mali reveals its response mechanism to the biocontrol actinomycete Saccharothrix yanglingensis Hhs.015.BMC microbiology · 2018Article
- Two members of the velvet family, VmVeA and VmVelB, affect conidiation, virulence and pectinase expression in Valsa mali.Molecular plant pathology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Valsa mali var. mali (Vmm), the causal agent of apple tree canker disease, produces various toxic compounds, including protocatechuic acid, p-hydroxybenzoic acid, p-hydroxyacetophenone, 3-(p-hydroxyphenyl)propanoic acid and phloroglucinol. Here, we examined the relationship between toxin production and the pathogenicity of Vmm strains and determined their bioactivities in several assays, for further elucidating the pathogenesis mechanisms of Vmm and for developing new procedures to control this disease. The toxins were quantified with the high performance liquid chromatography (HPLC) method, and the results showed that the strain with attenuated virulence produced low levels of toxins with only three to four kinds of compounds being detectable. In contrast, higher amounts of toxins were produced by the more aggressive strain, and all five compounds were detected. This indicated a significant correlation between the pathogenicity of Vmm strains and their ability to produce toxins. However, this correlation only existed in planta, but not in vitro. During the infection of Vmm, protocatechuic acid was first detected at three days post inoculation (dpi), and the others at seven or 11 dpi. In addition, all compounds produced noticeable symptoms on host plants at concentrations of 2.5 to 40 mmol/L, with protocatechuic acid being the most effective compound, whereas 3-(p-hydroxyphenyl)propanoic acid or p-hydroxybenzoic acid were the most active compounds on non-host plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.