Evidence map›Paper›PMID 24661686›Full record

ArticleDiagnostic microbiology and infectious disease2014

Performance of a rapid multi-analyte 2-photon excitation assay in children with acute respiratory infection.

Pedro Brotons, Cristian Launes, Melania Iñigo, Natalia Peris, Laura Selva, Carmen Muñoz-Almagro

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro BrotonsDepartment of Microbiology, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain.
Cristian LaunesDepartment of Paediatrics, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain.
Melania IñigoDepartment of Microbiology, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain.
Natalia PerisDepartment of Microbiology, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain.
Laura SelvaDepartment of Microbiology, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain.
Carmen Muñoz-AlmagroDepartment of Microbiology, Hospital Sant Joan de Deu and University of Barcelona, Passeig Sant Joan de Deu, 08950 Esplugues, Barcelona, Spain. Electronic address: cma@hsjdbcn.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to evaluate the diagnostic performance of the novel 2-photon excitation-based mariPOC© Assay (ArcDia Laboratories, Turku, Finland) for antigen detection of respiratory viruses versus real-time polymerase chain reaction (PCR). The mariPOC Assay and 2 multiplex real-time PCR techniques were performed on nasopharyngeal samples from pediatric patients with suspicion of acute respiratory infection admitted to a children's hospital in Spain during October 2011 to January 2013. A total of 233 samples were studied. Sensitivities and specificities (95% confidence interval) of the mariPOC Assay were for respiratory syncytial virus (RSV), 78.4% (69.7-85.6) and 99.2% (96.3-100.0); influenza virus (IFV) A, 66.7% (26.2-94.0) and 99.6% (97.9-100.0); IFV-B, 63.6% (33.6-87.2) and 100.0% (98.7-100.0); human metapneumovirus (hMPV), 60.0% (34.5-81.9) and 100.0% (98.6-100.0); adenovirus (ADV), 12.5% (0.6-48.0) and 100.0% (98.7-100.0), respectively. The mariPOC Assay is a highly specific method for simultaneous detection of 8 respiratory viruses but has sensitivities that range from moderately high for RSV to moderate for IFV and hMPV and low for ADV.

Indexed as

AdolescentAntigens, ViralChildChild, PreschoolClinical Laboratory TechniquesHospitals, PediatricHumansImmunoassayMultiplex Polymerase Chain ReactionNasopharynxReal-Time Polymerase Chain ReactionRespiratory Tract InfectionsSensitivity and SpecificitySpainVirus DiseasesAntigens, ViralAntigen detectionChildrenPoint-of-careRapid testingRespiratory infection

Identifiers

PMID24661686
PMCPMC7132766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.