Evidence map›Paper›PMID 24661392›Full record

ArticleDrug and alcohol dependence2014

Characteristics of people who initiate injection drug use later in life.

Sonya Arreola, Ricky N Bluthenthal, Lynn Wenger, Daniel Chu, James Thing, Alex H Kral

Abstract readComparative Study
In one paragraph

Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sonya ArreolaGlobal Forum on MSM and HIV, 436 14th Street, Suite 1500, Oakland, CA 94612, United States. Electronic address: ArreolaResearch@gmail.com.
Ricky N BluthenthalDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, United States.
Lynn WengerUrban Health Program, RTI International, 351 California St., San Francisco, CA 94104, United States.
Daniel ChuDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, United States.
James ThingDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, United States.
Alex H KralUrban Health Program, RTI International, 351 California St., San Francisco, CA 94104, United States.

Funding

Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Exploratory Research on Late Initiation of Drug InjectionR01DA027689 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BLUTHENTHAL, RICKY N, KRAL, ALEXANDER H · 2010 to 2012
$1.7M
NICHD NIH HHS R25 HD045810NIDA NIH HHS R01 DA027689NIDA NIH HHS R01-DA027689
6 · The paper itself

Abstract

backgroundStudies report that among people who inject drugs (PWID), approximately 1 in 7 initiated injection during their thirties or later (referred to hereafter as "late initiates"). However, little is known about individuals who are late initiates. This study aims to describe characteristics of late initiates to drug injection and to examine how they differ from people who initiated drug injection prior to the age of 30 ("typical initiates").

methodsWe recruited 696 active PWID in Los Angeles and San Francisco, California between 2011 and 2013, using targeted sampling and street outreach methods. Participants completed personal interviews that covered items on demographics, drug use history and practices, injection initiation episode, HIV injection- and sex-related risk, health care utilization among others. We used bivariate and multivariate analyses to examine factors associated being a late initiate.

resultsIn our sample, 19% of participants who were 30 years or older were classified as late initiates. In multivariate analysis controlling for city, late initiates had higher odds of being female and African American, having been in treatment prior to initiation, initiating illicit drug use at an older age, and being assisted into injection by someone of the same age or younger. Late initiates had lower odds of frequent recent injection, and having a bipolar disorder diagnosis.

conclusionLate initiates comprise a significant proportion of active PWIDs. More study on the health consequences of late initiation are needed as are interventions to prevent transition to drug injection among at-risk populations.

Indexed as

AdolescentAdultAge of OnsetAgingCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansLos AngelesMalePatient Acceptance of Health CareRisk FactorsSan FranciscoSubstance Abuse, IntravenousYoung AdultAgingEpidemiologyInjection drug usersInjection initiationPeople who inject drugsSubstance use

Identifiers

PMID24661392
PMCPMC4035351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.