Evidence map›Paper›PMID 24661096›Full record

ReviewChemical reviews2014

Protein design: toward functional metalloenzymes.

Fangting Yu, Virginia M Cangelosi, Melissa L Zastrow, Matteo Tegoni, Jefferson S Plegaria, Alison G Tebo, Catherine S Mocny, Leela Ruckthong, Hira Qayyum, Vincent L Pecoraro

Abstract readReview
In one paragraph

Review in Chemical reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed.

  1. Article
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  13. Review
  14. Article
  15. Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Classifying metal-binding sites with neural networks.Protein science : a publication of the Protein Society · 2023
    Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fangting YuUniversity of Michigan , Ann Arbor, Michigan 48109, United States.
Virginia M Cangelosi
Melissa L Zastrow
Matteo Tegoni
Jefferson S Plegaria
Alison G Tebo
Catherine S Mocny
Leela Ruckthong
Hira Qayyum
Vincent L Pecoraro

Funding

MICHIGAN CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008597 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONTGOMERY, JOHN · 1996 to 2018
$5.0M
Toxic Metal Complexation By de Novo Designed PeptidesR01ES012236 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PECORARO, VINCENT L · 2003 to 2018
$4.4M
Active Site Modifications in De Novo Designed MetalloenzymesF32GM100543 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CANGELOSI, VIRGINIA MAY · 2012 to 2014
$118k
NIEHS NIH HHS R01 ES012236NIGMS NIH HHS F32 GM100543NIGMS NIH HHS T32 GM008597
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine DeaminaseAlkenesAnimalsDNAHemeMetalloproteinsMetals, HeavyProtein BindingProtein EngineeringProtein Structure, TertiaryZinc FingersAdenosine DeaminaseAlkenesDNAHemeMetalloproteinsMetals, Heavy

Identifiers

PMID24661096
PMCPMC4300145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.