Evidence map›Paper›PMID 24661004›Full record

ArticleJournal of neurochemistry2014

LRRK2: dropping (kinase) inhibitions and seeking an (immune) response.

Adamantios Mamais, Mark R Cookson

Abstract readEditorialComment
In one paragraph

Article in Journal of neurochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Exploring the focal role of LRRK2 kinase in Parkinson's disease.Environmental science and pollution research international · 2022
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Adamantios MamaisCell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
Mark R Cookson

Funding

Leucine rich repeat kinase 2 and dominantly inherited Parkinson diseaseZIAAG000948 · NIA · NATIONAL INSTITUTE ON AGING · PI COOKSON, MARK · 2009 to 2025
$18.3M
Leucine rich repeat kinase 2 and dominantly inherited Parkinson diseaseZ01AG000948 · NIA · NATIONAL INSTITUTE ON AGING · PI COOKSON, MARK · 2008 to 2008
$767k
Intramural NIH HHS Z01 AG000948
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansInterferon-gammaLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MacrophagesMitogen-Activated Protein Kinase 7Protein Serine-Threonine KinasesInterferon-gammaLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LRRK2 protein, humanMitogen-Activated Protein Kinase 7Protein Serine-Threonine Kinases

Identifiers

PMID24661004
PMCPMC4055502

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.