ArticleAnesthesiology and pain medicine2014
Comparison between the effects of alfentanil, fentanyl and sufentanil on hemodynamic indices during rapid sequence intubation in the emergency department.
Article in Anesthesiology and pain medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Comparison of Intravenous Dexmedetomidine versus Esmolol for Attenuation of Hemodynamic Response to Tracheal Intubation after Rapid Sequence Induction: A Systematic Review and Meta-Analysis.BioMed research international · 2019Pooled it
- Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials.Critical care (London, England) · 2018Pooled it
- Comparison of anesthetic effects of different doses of alfentanil combined with ciprofol in elderly patients undergoing ERCP: a randomized controlled trial.BMC anesthesiology · 2023Trial
- Clinical effect of different doses of ciprofol for induction of general anesthesia in elderly patients: A randomized, controlled trial.Pharmacology research & perspectives · 2023Trial
- Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial.Drug design, development and therapy · 2023Trial
- Effect of low-dose ketamine versus fentanyl on attenuating the haemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing general anaesthesia: a prospective, double-blinded, randomised controlled trial.African health sciences · 2019Trial
- Peri-intubation Cardiovascular Collapse During Emergency Airway Management.Pulmonary therapy · 2025Review
- Commentary: Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients.Frontiers in pharmacology · 2025Article
- Comparison of a single intravenous infusion of alfentanil or sufentanil combined with target-controlled infusion of propofol for daytime hysteroscopy: a randomized clinical trial.Therapeutic advances in drug safety · 2024Article
- Effects of Fentanyl Versus Remifentanil Pretreatment on the QTc Interval in Patients Undergoing Rapid Sequence Intubation: A Randomized Clinical Trial.Anesthesiology and pain medicine · 2022Article
- Effects of Short-Acting Opioids on Intraocular Pressure during General Anesthesia: Systematic Review and Network Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Feasibility of using oxycodone as the sole opioid for induction and maintenance of general anaesthesia in minor/moderate surgery: a prospective, observational, descriptive study.The Journal of international medical research · 2020Observational
- Rapid sequence induction (RSI) in trauma patients: Insights from healthcare providers.World journal of emergency medicine · 2019Article
- Comparison of Three Techniques on Facility of Bag-Mask Ventilation: Thenar Eminence, E-O and E-C.Anesthesiology and pain medicine · 2018Article
- Diagnostic Value of Sonography for Confirmation of Endotracheal Intubation in the Emergency Department.Anesthesiology and pain medicine · 2017Article
- Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting).World journal of surgery · 2017Review
- Comparison of tracheal tube cuff pressure with two techniques: fixed volume versus pilot balloon palpation.Journal of cardiovascular and thoracic research · 2017Article
- Effect of Neck Collar Fixation on Ventilation in Multiple Trauma Patients.Trauma monthly · 2016Article
- Effective Bolus Dose of Sufentanil to Attenuate Cardiovascular Responses in Laryngoscopic Double-Lumen Endobronchial Intubation.Anesthesiology and pain medicine · 2016Article
- Opioid Drugs in Patients With Liver Disease: A Systematic Review.Hepatitis monthly · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaryngoscopy and tracheal intubation lead to the alteration of hemodynamic parameters, including blood pressure and heart rate, in traumatic patients who sustain rapid sequence intubation (RSI). Various drugs such as fentanyl, alfentanil and sufentanil have been used to modify these hemodynamic responses.
objectivesThe aim of the present study is to compare the effects of fentanyl, sufentanil and alfentanil in trauma patients who require RSI in the emergency department (ED). PATIENTS AND
methodsThis was a randomized double-blinded study conducted on 90 patients (18-65 years old, ASA I, II), who needed intubation following trauma. The patients were randomly divided into three groups, Group I, Group II and Group III, who have received alfentanil, fentanyl and sufentanil, respectively. Heart rate, blood pressure, saturation of peripheral oxygen and end-tidal carbon dioxide were measured 5 minutes before and 3, 5 and 10 minutes after intubation, respectively. The changes of the hemodynamic parameters were compared in between groups. Data were analyzed by One-way ANOVA, General Linear Model Repeated Measure and Mauchly's Sphericity Test. A P < 0.05 was considered statistically significant.
resultsThere was no significant statistical difference among groups with respect to hemodynamic parameters.
conclusionsAlfentanil, fentanyl and sufentanil can be used safely as premedication drugs for trauma patients who need intubation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.