ArticleExperimental and therapeutic medicine2014
Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.
Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- The P38MAPK/ATF2 signaling pathway is involved in PND in mice.Experimental brain research · 2024Article
- Splenectomy does not affect mouse behaviors.Neural regeneration research · 2023Article
- Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis.European journal of histochemistry : EJH · 2023Article
- Molecular Mechanism ofFrontiers in aging neuroscience · 2022Article
- Determination of Senegenin and Tenuifolin in Mouse Blood by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry and Their Pharmacokinetics.International journal of analytical chemistry · 2022Article
- Intervention of NF-Κb Signaling Pathway and Preventing Post-Operative Cognitive Dysfunction as Well as Neuronal Apoptosis.Iranian journal of public health · 2022Article
- Insulin-like growth factor-1 improves postoperative cognitive dysfunction following splenectomy in aged rats.Experimental and therapeutic medicine · 2021Article
- The Non-peptide Angiotensin-(1-7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats.Frontiers in aging neuroscience · 2021Article
- Jianpi Jieyu Decoction, An Empirical Herbal Formula, Exerts Psychotropic Effects in Association With Modulation of Gut Microbial Diversity and GABA Activity.Frontiers in pharmacology · 2021Article
- Protective Effects and Mechanism of Radix Polygalae Against Neurological Diseases as Well as Effective Substance.Frontiers in psychiatry · 2021Review
- Amantadine attenuates sepsis-induced cognitive dysfunction possibly not through inhibiting toll-like receptor 2.Journal of molecular medicine (Berlin, Germany) · 2018Article
- Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.Behavioural brain research · 2017Review
- TNF-α receptor antagonist attenuates isoflurane-induced cognitive impairment in aged rats.Experimental and therapeutic medicine · 2016Article
- Senegenin Ameliorate Acute Lung Injury Through Reduction of Oxidative Stress and Inhibition of Inflammation in Cecal Ligation and Puncture-Induced Sepsis Rats.Inflammation · 2016Article
- The Cox-2 Inhibitor Meloxicam Ameliorates Neuroinflammation and Depressive Behavior in Adult Mice after Splenectomy.Journal of neurophysiology and neurological disorders · 2016Article
- Neuroinflammation in the normal aging hippocampus.Neuroscience · 2015Review
- Intracisternal administration of an interleukin-6 receptor antagonist attenuates surgery-induced cognitive impairment by inhibition of neuroinflammatory responses in aged rats.Experimental and therapeutic medicine · 2015Article
Corrections and comments
- Retraction · 2023-10-23Author Unresponsive · Concerns/Issues about Image · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · · see also: https://docs.google.com/spreadsheets/d/1I7uuhZ7NgMtzXFaJVfBPzP92JjCHO8tJDOjL8Y_9q1U/edit?usp=sharing
- Retracted
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative cognitive dysfunction (POCD) is common in elderly patients. Senegenin, an active component of extracts from
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.