ArticleFrontiers in neuroscience2014
BOLD fMRI signal characteristics of S1- and S2-SSFP at 7 Tesla.
Article in Frontiers in neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Red Blood Cell-Encapsulated Nanoparticles for Long-Circulating, Improved Specificity Functional MRI.Chemical & biomedical imaging · 2026Article
- Impact of vascular architecture, oxygen saturation, and hematocrit on human cortical depth-dependent GE- and SE-BOLD fMRI signals: A simulation approach using realistic 3D vascular networks.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- An in-vivo study of BOLD laminar responses as a function of echo time and static magnetic field strength.Scientific reports · 2021Article
- Robust functional mapping of layer-selective responses in human lateral geniculate nucleus with high-resolution 7T fMRI.Proceedings. Biological sciences · 2020Article
- Pulse sequences and parallel imaging for high spatiotemporal resolution MRI at ultra-high field.NeuroImage · 2018Review
- Integrated SSFP for functional brain mapping at 7T with reduced susceptibility artifact.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- Variable flip angle 3D-GRASE for high resolution fMRI at 7 tesla.Magnetic resonance in medicine · 2016Article
- Toward 20 T magnetic resonance for human brain studies: opportunities for discovery and neuroscience rationale.Magma (New York, N.Y.) · 2016Review
- Sub-millimeter T2 weighted fMRI at 7 T: comparison of 3D-GRASE and 2D SE-EPI.Frontiers in neuroscience · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectTo compare the BOLD fMRI signal characteristics at in the cortex and on the pial surface for a non-balanced steady-state free precession sequence (nb-SSFP) at 7 T. MATERIALS AND
methodsA multi-echo nb-SSFP sequence was used for high resolution fMRI at 7 T. Two S1 (S(+)) echoes at different echo times were acquired together with an S2 (S(-)) echo. The primary visual cortex (V1) was examined using a reversing checkerboard paradigm at an isotropic resolution of 0.75 mm, with 35 volumes acquired and a total scan time of 27 min.
resultsSignificant activation was observed in all subjects for all three acquired echoes. For the S1 signal at the longer TE, the activation induced signal change was about 4% in the cortex and 10% at the cortical surface, while for S2 the corresponding values were 3 and 5%.
conclusionFor both S1 and S2 data, the BOLD signal peaks at the pial surface. The large pial surface signal change in S2 may be caused by dynamic averaging around post-capillary vessels embedded within CSF. This is made possible by the long diffusion times of the pathways contributing to the S2 signal and the relatively high diffusion coefficient of CSF. The results indicate that S2-SSFP might not be a suited alternative to spin-echo for high-resolution fMRI at 7 T.
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