Evidence map›Paper›PMID 24659943›Full record

ReviewTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2014

Emerging Pathogens - How Safe is Blood?

Michael Schmidt, Wolf-Jochen Geilenkeuser, Walid Sireis, Erhard Seifried, Kai Hourfar

Open access · bronzeAbstract readReview
In one paragraph

Review in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Pathogens (Basel, Switzerland) · 2023
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Selective Testing of At-Risk Blood Donors for Trypanosoma cruzi and Plasmodium spp. in Switzerland.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016
    Article
  7. Review
  8. Article
  9. Article
  10. Transfusion safety from the viewpoint of a musical quintet.Blood transfusion = Trasfusione del sangue · 2015
    Article
  11. Article
  12. Legal and ethical issues in safe blood transfusion.Indian journal of anaesthesia · 2014
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael SchmidtReference Institute for Bioanalytics, Bonn, Goethe University, Frankfurt/M., Germany.
Wolf-Jochen GeilenkeuserReference Institute for Bioanalytics, Bonn, Goethe University, Frankfurt/M., Germany.
Walid SireisGerman Red Cross, Baden-Wuerttemberg - Hessen, Institute of Transfusion Medicine and Immuno-hemotherapy, Goethe University, Frankfurt/M., Germany.
Erhard SeifriedGerman Red Cross, Baden-Wuerttemberg - Hessen, Institute of Transfusion Medicine and Immuno-hemotherapy, Goethe University, Frankfurt/M., Germany.
Kai HourfarGerman Red Cross, Baden-Wuerttemberg - Hessen, Institute of Transfusion Medicine and Immuno-hemotherapy, Goethe University, Frankfurt/M., Germany.
German Red Cross · DEGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last few decades, blood safety efforts were mainly focused on preventing viral infections. However, humanity's increased mobility and improved migration pathways necessitate a global perspective regarding other transfusion-transmitted pathogens. This review focuses on the general infection risk of blood components for malaria, dengue virus, Trypanosoma cruzi (Chagas disease) and Babesia spp. Approximately 250 million people become infected by Plasmodium spp. per year. Dengue virus affects more than 50 million people annually in more than 100 countries; clinically, it can cause serious diseases, such as dengue haemorrhagic fever and dengue shock syndrome. Chagas disease, which is caused by Trypanosoma cruzi, mainly occurs in South America and infects approximately 10 million people annually. Babesia spp. is a parasitic infection that infects red blood cells; although many infections are asymptomatic, severe clinical disease has been reported, especially in the elderly. Screening assays are available for all considered pathogens but make screening strategies more complex and more expensive. A general pathogen inactivation for all blood components (whole blood) promises to be a long-term, sustainable solution for both known and unknown pathogens. Transfusion medicine therefore eagerly awaits such a system.

Indexed as

BabesiaBlood safetyChagas diseaseDengue virusMalaria

Identifiers

PMID24659943
PMCPMC3949612
OpenAlexW1977737688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.