Evidence map›Paper›PMID 24659576›Full record

SynthesisEnvironmental health perspectives2014

Water distribution system deficiencies and gastrointestinal illness: a systematic review and meta-analysis.

Ayse Ercumen, Joshua S Gruber, John M Colford

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Environmental health perspectives, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Acute Diarrheal Disease Associated With Climate Variability and Water Supply System Configuration: An Ecological Study in Brazil.Water environment research : a research publication of the Water Environment Federation · 2026
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  14. Racial and ethnic disparities in access to safe water and sanitation in high-income countries: a case study among the Arab-Bedouins of Southern Israel.Journal of water, sanitation, and hygiene for development : a journal of the International Water Association · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ayse ErcumenDivision of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, California, USA.
Joshua S Gruber
John M Colford

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWater distribution systems are vulnerable to performance deficiencies that can cause (re)contamination of treated water and plausibly lead to increased risk of gastrointestinal illness (GII) in consumers.

objectivesIt is well established that large system disruptions in piped water networks can cause GII outbreaks. We hypothesized that routine network problems can also contribute to background levels of waterborne illness and conducted a systematic review and meta-analysis to assess the impact of distribution system deficiencies on endemic GII.

methodsWe reviewed published studies that compared direct tap water consumption to consumption of tap water re-treated at the point of use (POU) and studies of specific system deficiencies such as breach of physical or hydraulic pipe integrity and lack of disinfectant residual.

resultsIn settings with network malfunction, consumers of tap water versus POU-treated water had increased GII [incidence density ratio (IDR) = 1.34; 95% CI: 1.00, 1.79]. The subset of nonblinded studies showed a significant association between GII and tap water versus POU-treated water consumption (IDR = 1.52; 95% CI: 1.05, 2.20), but there was no association based on studies that blinded participants to their POU water treatment status (IDR = 0.98; 95% CI: 0.90, 1.08). Among studies focusing on specific network deficiencies, GII was associated with temporary water outages (relative risk = 3.26; 95% CI: 1.48, 7.19) as well as chronic outages in intermittently operated distribution systems (odds ratio = 1.61; 95% CI: 1.26, 2.07).

conclusionsTap water consumption is associated with GII in malfunctioning distribution networks. System deficiencies such as water outages also are associated with increased GII, suggesting a potential health risk for consumers served by piped water networks.

Indexed as

Drinking WaterGastrointestinal DiseasesHumansIncidenceWater PurificationWater SupplyDrinking Water

Identifiers

PMID24659576
PMCPMC4080524

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.