ArticleJournal of experimental botany2014
The transcription factor AREB1 regulates primary metabolic pathways in tomato fruits.
Article in Journal of experimental botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 82 citations in OpenAlex.
- Molecular orchestration of malate and citrate metabolism: regulatory networks governing organic acid dynamics and fruit quality attributes.Horticulture research · 2026Article
- SlAREB1 regulates ethylene biosynthesis and mediates the effect of abscisic acid on postharvest ripening of tomato fruit.Frontiers in plant science · 2026Article
- What metabolomics has taught us about tomato fruit ripening and quality.Journal of experimental botany · 2025Review
- Nontoxic mesoporous silica nanoparticles protect Physcomitrium patens against salt stress.Stress biology · 2025Article
- Multi-omics dissection of metabolic and transcriptional regulation underlying fruit maturation in Panax ginseng.BMC plant biology · 2025Article
- Genome-wide identification and molecular characterization of the MAPK family members in sand pear (Pyrus pyrifolia).BMC genomics · 2025Article
- Comprehensive Identification ofInternational journal of molecular sciences · 2025Article
- Recent Advances in Postharvest Application of Exogenous Phytohormones for Quality Preservation of Fruits and Vegetables.Plants (Basel, Switzerland) · 2024Review
- Genome-wide identification, characterization and expression analysis of theFrontiers in plant science · 2024Article
- ABRE-BINDING FACTOR3-WRKY DNA-BINDING PROTEIN44 module promotes salinity-induced malate accumulation in pear.Plant physiology · 2023Article
- ChIP-Seq Analysis ofFoods (Basel, Switzerland) · 2023Article
- PANTOTHENATE KINASE4, LOSS OF GDU2, and TRANSPOSON PROTEIN1 affect the canalization of tomato fruit metabolism.Plant physiology · 2023Article
- Participation of FaTRAB1 Transcription Factor in the Regulation ofFoods (Basel, Switzerland) · 2023Article
- Abscisic acid biosynthesis, metabolism and signaling in ripening fruit.Frontiers in plant science · 2023Review
- Comparative transcriptomics of wild and commercial Citrus during early ripening reveals how domestication shaped fruit gene expression.BMC plant biology · 2022Article
- The metabolic changes that effect fruit quality during tomato fruit ripening.Molecular horticulture · 2022Review
- Abscisic Acid: Role in Fruit Development and Ripening.Frontiers in plant science · 2022Review
- Effect of long-term drought on tomato leaves: the impact on metabolic and antioxidative response.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Genome-wide identification and characterization of bZIP transcription factors and their expression profile under abiotic stresses in Chinese pear (Pyrus bretschneideri).BMC plant biology · 2021Article
- The interplay between ABA/ethylene and NAC TFs in tomato fruit ripening: a review.Plant molecular biology · 2021Review
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tomato fruit development is regulated both by the action of plant hormones and by tight genetic control. Recent studies suggest that abscisic acid (ABA) signalling may affect different aspects of fruit maturation. Previously, it was shown that SlAREB1, an ABA-regulated transcription factor involved in stress-induced responses, is expressed in seeds and in fruit tissues in tomato. Here, the role of SlAREB1 in regulating the expression of genes relevant for primary metabolic pathways and affecting the metabolic profile of the fruit was investigated using transgenic tomato lines. Metabolite profiling using gas chromatography-time of flight mass spectrometry (GC-TOF-MS) and non-targeted liquid chromatography-mass spectrometry (LC-MS) was performed on pericarp tissue from fruits harvested at three stages of fruit development. Principal component analysis of the data could distinguish the metabolite profiles of non-transgenic fruits from those that overexpress and down-regulate SlAREB1. Overexpression of SlAREB1 resulted in increased content of organic acids, hexoses, hexose-phosphates, and amino acids in immature green, mature green, and red ripe fruits, and these modifications correlated with the up-regulation of enzyme-encoding genes involved in primary carbohydrate and amino acid metabolism. A non-targeted LC-MS analysis indicated that the composition of secondary metabolites is also affected in transgenic lines. In addition, gene expression data revealed that some genes associated with fruit ripening are also up-regulated in SlAREB1-overexpressing lines compared with wild-type and antisense lines. Taken together, the results suggest that SlAREB1 participates in the regulation of the metabolic programming that takes place during fruit ripening and that may explain part of the role of ABA in fruit development in tomato.
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