Evidence map›Paper›PMID 24659331›Full record

ArticleClinical rheumatology2014

Serum amyloid-A in Behçet's disease.

Antonio Vitale, Donato Rigante, Giuseppe Lopalco, Maria Giuseppina Brizi, Francesco Caso, Rossella Franceschini, Rosario Denaro, Mauro Galeazzi, Leonardo Punzi, Florenzo Iannone and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Biomarkers in Primary Systemic Vasculitides: Narrative Review.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Antonio VitaleResearch Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, Italy. cantariniluca@hotmail.com
Donato Rigante
Giuseppe Lopalco
Maria Giuseppina Brizi
Francesco Caso
Rossella Franceschini
Rosario Denaro
Mauro Galeazzi
Leonardo Punzi
Florenzo Iannone
Giovanni Lapadula
Antonella Simpatico
Edoardo Marrani
Luisa Costa
Rolando Cimaz
Luca Cantarini
University of Siena · ITUniversity of Florence · ITFederico II University Hospital · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum amyloid-A (SAA) is an acute phase protein, synthesized by the liver and previously investigated as a marker of disease activity in many rheumatologic disorders. Its significance in Behçet’s disease (BD), a chronic inflammatory disorder at the crossroad between autoimmune and autoinflammatory syndromes, is still unraveled. Our aim was to assess the role of SAA levels as a potential marker of disease activity in patients with BD. According to our findings, the occurrence of oral aphthosis, neurological impairment, and ocular disease is significantly associated with SAA serum levels higher than 30, 50, and 150 mg/L, respectively. We also suggest that increased SAA levels might identify a thrombotic risk in BD with previous or concurrent vascular involvement.

Indexed as

AdultBehcet SyndromeBiomarkersBlood SedimentationFemaleHumansMaleMiddle AgedSerum Amyloid A ProteinBiomarkersSerum Amyloid A Protein

Identifiers

PMID24659331
OpenAlexW1995964502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.