Evidence map›Paper›PMID 24659140›Full record

Trial reportClinical autonomic research : official journal of the Clinical Autonomic Research Society2014

Treadmill gait training improves baroreflex sensitivity in Parkinson's disease.

Mohan Ganesan, Pramod Kumar Pal, Anupam Gupta, Talakad N Sathyaprabha

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 7 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03815409 nacompletednot on this map

Rehabilitation of Parkinsonian Gait in Body Weight Support Combined With Treadmill: a Controlled Study

TypeinterventionalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2007 to 2008Enrolled36ConditionsParkinson's DiseaseArmsTreadmill with partial weight unload, Traditional PT rehabilitation treatment
NCT04251728 nacompletednot on this mapstarted 2022, after this paper: background citation

Chronic Effects of Automated Mechanical Peripheral Stimulation on Cardiovascular and Functional Variables in Patients With Parkinson's Disease

TypeinterventionalSponsorUniversidad Católica del MauleRan2022 to 2022Enrolled40ConditionsParkinson DiseaseArmsAutomated mechanical peripheral stimulation, Physical Exercise, SHAM
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 7 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Guideline
  7. Treadmill training for patients with Parkinson's disease.The Cochrane database of systematic reviews · 2015
    Pooled it
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Research in Parkinson's disease in India: A review.Annals of Indian Academy of Neurology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Mohan Ganesan
Pramod Kumar Pal
Anupam Gupta
Talakad N Sathyaprabha
National Institute of Mental Health and Neurosciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPartial weight supported treadmill gait training (PWSTT) is widely used in rehabilitation of gait in patient with Parkinson’s Diseases (PD). However, its effect on blood pressure variability (BPV) and baroreflex sensitivity (BRS) in PD has not been studied.

aimTo evaluate the effect of conventional and treadmill gait training on BPV components and BRS.

methodsSixty patients with idiopathic PD were randomized into three groups. Twenty patients in control group were on only stable medication, 20 patients in conventional gait training (CGT) group (Stable medication with CGT) and 20 patients in PWSTT group (Stable medication with 20 % PWSTT). The CGT and PWSTT sessions were given for 30 min per day, 4 days per week, for 4 weeks (16 sessions). Groups were evaluated in their best ‘ON’ states. The beat-to-beat finger blood pressure (BP) was recorded for 10 min using a Finometer instrument (Finapres Medical Systems, The Netherlands). BPV and BRS results were derived from artifact-free 5-min segments using Nevrocard software.

resultsBRS showed a significant group with time interaction (F = 6.930; p = 0.003). Post-hoc analysis revealed that PWSTT group showed significant improvement in BRS (p < 0.001) after 4 weeks of training. No significant differences found in BPV parameters; systolic BP, diastolic BP, co-variance of systolic BP and low frequency component of systolic BP.

conclusionsFour weeks of PWSTT significantly improves BRS in patients with PD. It can be considered as a non-invasive method of influencing BRS for prevention of orthostatic BP fall in patients with PD.

Indexed as

Exercise TherapyAgedAntiparkinson AgentsBaroreflexBlood PressureFemaleGaitHumansMaleMiddle AgedParkinson DiseasePostural BalanceTreatment OutcomeAntiparkinson Agents

Identifiers

PMID24659140
OpenAlexW1972073781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.