Evidence map›Paper›PMID 24658802›Full record

ArticleJournal of the American Society for Mass Spectrometry2014

Numerical modeling of ion transport in an ESI-MS system.

Natalia Gimelshein, Sergey Gimelshein, Taylor Lilly, Eugene Moskovets

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gas Flow and Ion Transfer in Heated ESI Capillary Interfaces.Journal of the American Society for Mass Spectrometry · 2018
    Article
  5. Article
  6. Gas Flow in the Capillary of the Atmosphere-to-Vacuum Interface of Mass Spectrometers.Journal of the American Society for Mass Spectrometry · 2017
    Article
  7. Gas Flow Dynamics in Inlet Capillaries: Evidence for non Laminar Conditions.Journal of the American Society for Mass Spectrometry · 2016
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Natalia Gimelshein
Sergey Gimelshein
Taylor Lilly
Eugene Moskovets
MassTech (United States) · USUniversity of Colorado Colorado Springs · USUniversity of Southern California · US

Funding

Fast fragmentation method for characterization of peptides with labile PTMsR43GM103358 · NIGMS · MASSTECH, INC. · PI MOSKOVETS, EUGENE · 2012 to 2012
$414k
NIGMS NIH HHS 1R43GM103358
6 · The paper itself

Abstract

Gas and ion transport in the capillary-skimmer subatmospheric interface of a mass spectrometer, which is typically utilized to separate unevaporated micro-droplets from ions, was studied numerically using a two-step approach spanning multiple gas dynamic regimes. The gas flow in the heated capillary and in the interface was determined by solving numerically the Navier-Stokes equation. The capillary-to-skimmer gas/ion flow was modeled through the solution of the full Boltzmann equation with a force term. The force term, together with calculated aerodynamic drag, determined the ion motion in the gap between the capillary and skimmer. Three-dimensional modeling of the impact of the voltage applied to the Einzel lens on the transmission of doubly charged peptide ions through the skimmer orifice was compared with experimental data obtained in the companion study. Good agreement between measured and computed signals was observed. The numerical results indicate that as many as 75% of the ions that exit from the capillary are lost on the conical surface of the skimmer or capillary outer surface because of the electrostatic force and plume divergence.

Indexed as

Models, ChemicalImaging, Three-DimensionalKineticsMicrochemistryOligopeptidesPeptidesSolventsSpectrometry, Mass, Electrospray IonizationSubstance PVacuumVolatilizationOligopeptidesPeptidesSolventsSubstance P

Identifiers

PMID24658802
OpenAlexW1973283597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.