Evidence map›Paper›PMID 24658777›Full record

ArticleJournal of biomedical optics2014

High-speed multispectral confocal biomedical imaging.

Gary E Carver, Sarah A Locknar, William A Morrison, V Krishnan Ramanujan, Daniel L Farkas

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gary E CarverOmega Optical Inc., 21 Omega Drive, Brattleboro, Vermont 05301.
Sarah A LocknarOmega Optical Inc., 21 Omega Drive, Brattleboro, Vermont 05301.
William A MorrisonOmega Optical Inc., 21 Omega Drive, Brattleboro, Vermont 05301.
V Krishnan RamanujanCedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048.
Daniel L FarkasUniversity of Southern California, Department of Biomedical Engineering, Los Angeles, California 90089dSpectral Molecular Imaging, 250 N. Robertson Boulevard, Beverly Hills, California 90211.
Omega Optics (United States) · USCedars-Sinai Medical Center · USUniversity of Southern California · US

Funding

Rapid In-vivo Cancer Detection via Multispectral Confocal Cellular ImagingR44CA124036 · NCI · OMEGA OPTICAL INC. · PI CARVER, GARY E · 2008 to 2011
$850k
NCI NIH HHS 5R44CA124036-03NCI NIH HHS R44 CA124036
6 · The paper itself

Abstract

A new approach for generating high-speed multispectral confocal images has been developed. The central concept is that spectra can be acquired for each pixel in a confocal spatial scan by using a fast spectrometer based on optical fiber delay lines. This approach merges fast spectroscopy with standard spatial scanning to create datacubes in real time. The spectrometer is based on a serial array of reflecting spectral elements, delay lines between these elements, and a single element detector. The spatial, spectral, and temporal resolution of the instrument is described and illustrated by multispectral images of laser-induced autofluorescence in biological tissues.

Indexed as

AnimalsFiber Optic TechnologyFluorescent DyesImage Processing, Computer-AssistedMiceMicroscopy, ConfocalNeoplasms, ExperimentalOptical ImagingRatsFluorescent Dyes

Identifiers

PMID24658777
PMCPMC3962271
OpenAlexW1994836490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.