Evidence map›Paper›PMID 24657843›Full record

ReviewMatrix biology : journal of the International Society for Matrix Biology2014

Matricellular proteins and biomaterials.

Aaron H Morris, Themis R Kyriakides

Open access · hybridAbstract readReview
In one paragraph

Review in Matrix biology : journal of the International Society for Matrix Biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Osteopontin: The Molecular Bridge between Fat and Cardiac-Renal Disorders.International journal of molecular sciences · 2020
    Review
  8. Emerging Roles of Matricellular Proteins in Systemic Sclerosis.International journal of molecular sciences · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2.Matrix biology : journal of the International Society for Matrix Biology · 2018
    Article
  15. The Membrane Attack Complex/Perforin Superfamily.Journal of molecular microbiology and biotechnology · 2017
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aaron H MorrisDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Themis R KyriakidesDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States; Department of Pathology, Yale University, New Haven, CT, United States; Vascular Biology and Therapeutics Program, Yale University, New Haven, CT, United States. Electronic address: themis.kyriakides@yale.edu.
Yale University · US

Funding

Surgery / Physiology CoreP01HL107205 · NHLBI · YALE UNIVERSITY · PI SIMONS, MICHAEL · 2012 to 2022
$18.8M
MCP-1 and attenuation of the foreign body responseR01GM072194 · NIGMS · YALE UNIVERSITY · PI KYRIAKIDES, THEMIS R · 2005 to 2018
$4.7M
NHLBI NIH HHS HL107205NHLBI NIH HHS P01 HL107205NIGMS NIH HHS GM072194NIGMS NIH HHS R01 GM072194
6 · The paper itself

Abstract

Biomaterials are essential to modern medicine as components of reconstructive implants, implantable sensors, and vehicles for localized drug delivery. Advances in biomaterials have led to progression from simply making implants that are nontoxic to making implants that are specifically designed to elicit particular functions within the host. The interaction of implants and the extracellular matrix during the foreign body response is a growing area of concern for the field of biomaterials, because it can lead to implant failure. Expression of matricellular proteins is modulated during the foreign body response and these proteins interact with biomaterials. The design of biomaterials to specifically alter the levels of matricellular proteins surrounding implants provides a new avenue for the design and fabrication of biomimetic biomaterials.

Indexed as

Models, BiologicalBiocompatible MaterialsCCN Intercellular Signaling ProteinsCell Adhesion MoleculesExtracellular Matrix ProteinsForeign-Body ReactionHumansOsteonectinOsteopontinTenascinThrombospondinsBiocompatible MaterialsCCN Intercellular Signaling ProteinsCell Adhesion MoleculesExtracellular Matrix ProteinsOsteonectinOsteopontinPOSTN protein, humanSPARC protein, humanTenascinThrombospondinsBiocompatibleBiomaterialsDecellularizationExtracellular matrixForeign body responseMatricellular

Identifiers

PMID24657843
PMCPMC4167162
OpenAlexW2073124826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.