Evidence map›Paper›PMID 24657516›Full record

ArticleEnvironmental research2014

Association of short-term increases in ambient air pollution and timing of initial asthma diagnosis among Medicaid-enrolled children in a metropolitan area.

Judy K Wendt, Elaine Symanski, Thomas H Stock, Wenyaw Chan, Xianglin L Du

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Ambient air pollution sensitivity and severity of pediatric asthma.Journal of exposure science & environmental epidemiology · 2024
    Article
  3. Article
  4. The role of gene-ambient air pollution interactions in paediatric asthma.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  5. Article
  6. CC16 Levels into Adult Life Are Associated with Nitrogen Dioxide Exposure at Birth.American journal of respiratory and critical care medicine · 2019
    Article
  7. Sex Modifies Acute Ozone-Mediated Airway Physiologic Responses.Toxicological sciences : an official journal of the Society of Toxicology · 2019
    Article
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Effect of exposure to ambient PMJournal of biomedical research · 2017
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Judy K WendtSouthwest Center for Occupational and Environmental Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA; Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA.
Elaine SymanskiSouthwest Center for Occupational and Environmental Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA; Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA. Electronic address: Elaine.Symanski@uth.tmc.edu.
Thomas H StockSouthwest Center for Occupational and Environmental Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA; Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA.
Wenyaw ChanSouthwest Center for Occupational and Environmental Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA; Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA.
Xianglin L DuSouthwest Center for Occupational and Environmental Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA; Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, 1200 Herman Pressler Dr., Houston, TX 77030, USA.
Southwest Center for Educational Excellence · USThe University of Texas Health Science Center at Houston · US

Funding

Southwest Center for Occupational and Environmental HealthT42OH008421 · OH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FELKNOR, SARAH A. · 2005 to 2024
$24.1M
ACL HHS T42OH008421NIOSH CDC HHS 2T42OH008421NIOSH CDC HHS T42 OH008421
6 · The paper itself

Abstract

objectiveWe investigated associations of short-term changes in ambient ozone (O3), fine particulate matter (PM2.5) and nitrogen dioxide (NO2) concentrations and the timing of new-onset asthma, using a large, high-risk population in an area with historically high ozone levels.

methodsThe study population included 18,289 incident asthma cases identified among Medicaid-enrolled children in Harris County Texas between 2005-2007, using Medicaid Analytic Extract enrollment and claims files. We used a time-stratified case-crossover design and conditional logistic regression to assess the effect of increased short-term pollutant concentrations on the timing of asthma onset.

resultsEach 10 ppb increase in ozone was significantly associated with new-onset asthma during the warm season (May-October), with the strongest association seen when a 6-day cumulative average period was used as the exposure metric (odds ratio [OR]=1.05, 95% confidence interval [CI], 1.02-1.08). Similar results were seen for NO2 and PM2.5 (OR=1.07, 95% CI, 1.03-1.11 and OR=1.12, 95% CI, 1.03-1.22, respectively), and PM2.5 also had significant effects in the cold season (November-April), 5-day cumulative lag (OR=1.11. 95% CI, 1.00-1.22). Significantly increased ORs for O3 and NO2 during the warm season persisted in co-pollutant models including PM2.5. Race and age at diagnosis modified associations between ozone and onset of asthma.

conclusionOur results indicate that among children in this low-income urban population who developed asthma, their initial date of diagnosis was more likely to occur following periods of higher short-term ambient pollutant levels.

Indexed as

AdolescentAir PollutionAsthmaChildChild, PreschoolFemaleHumansInfantMaleMedicaidNitrogen DioxideOzoneParticulate MatterUnited StatesUrban PopulationNitrogen DioxideOzoneParticulate MatterAir pollutionAsthmaChildIncidenceMedicaid

Identifiers

PMID24657516
PMCPMC4502952
OpenAlexW2027197529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.