Evidence map›Paper›PMID 24657310›Full record

Trial reportBehaviour research and therapy2014

Family-based exposure and response prevention therapy for preschool-aged children with obsessive-compulsive disorder: a pilot randomized controlled trial.

Adam B Lewin, Jennifer M Park, Anna M Jones, Erika A Crawford, Alessandro S De Nadai, Jessie Menzel, Elysse B Arnold, Tanya K Murphy, Eric A Storch

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01447966 (Family Based Cognitive-Behavioral Treatment for Preschoolers With Obsessive Compulsive Disorder), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01447966 nacompletednot on this map

Family Based Cognitive-Behavioral Treatment for Preschoolers With Obsessive Compulsive Disorder

TypeinterventionalSponsorUniversity of South FloridaRan2011 to 2014Enrolled31ConditionsObsessive Compulsive Disorder (OCD)ArmsCognitive Behavioral Therapy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adam B LewinDepartment of Pediatrics, University of South Florida, USA; Department of Psychology, University of South Florida, USA; Department of Psychiatry & Behavioral Neurosciences, University of South Florida, USA. Electronic address: alewin@health.usf.edu.
Jennifer M ParkDepartment of Psychology, University of South Florida, USA.
Anna M JonesDepartment of Psychology, University of South Florida, USA.
Erika A CrawfordDepartment of Pediatrics, University of South Florida, USA.
Alessandro S De NadaiDepartment of Psychology, University of South Florida, USA.
Jessie MenzelDepartment of Psychology, University of South Florida, USA.
Elysse B ArnoldDepartment of Pediatrics, University of South Florida, USA; Department of Psychology, University of South Florida, USA.
Tanya K MurphyDepartment of Pediatrics, University of South Florida, USA; Department of Psychiatry & Behavioral Neurosciences, University of South Florida, USA.
Eric A StorchDepartment of Pediatrics, University of South Florida, USA; Department of Psychology, University of South Florida, USA; Department of Psychiatry & Behavioral Neurosciences, University of South Florida, USA.
University of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo examine the feasibility, acceptability and preliminary efficacy of family-based exposure/response prevention therapy (E/RP) versus treatment as usual (TAU) in a cohort of very young children with early onset obsessive-compulsive disorder (OCD).

methodsThirty-one children ages 3-8 years (M = 5.8 years) with a primary diagnosis of OCD were randomized to E/RP or TAU. The E/RP condition received 12 sessions of family-based E/RP twice weekly over 6 weeks. Families were assessed at baseline, post-treatment, 1-month and 3-month follow up. The Children's Yale Brown Obsessive Compulsive Scale and Clinical Global Impression served as primary outcome measures.

resultsA large group effect emerged in favor of the E/RP group (d = 1.69). Sixty-five percent of the E/RP group was considered treatment responders as compared to 7% in the TAU group. Symptom remission was achieved in 35.2% of the E/RP group and 0% of the TAU group. There was no attrition and satisfaction was high; gains were maintained at 3 months.

conclusionsEven amongst children as young as 3 years, developmentally tailored E/RP is efficacious and well-tolerated in reducing OCD symptoms. Key adaptations for younger children include extensive parent involvement, targeting family accommodation, and frequent meetings while delivering a full course of E/RP. CLINICALTRIALSGOV IDENTIFIER: NCT01447966 http://clinicaltrials.gov/ct2/show/NCT01447966?term=ocd+and+st+petersburg&rank=1.

Indexed as

Behavior TherapyFamily TherapyImplosive TherapyAge FactorsChildChild, PreschoolCombined Modality TherapyFemaleHumansMaleObsessive-Compulsive DisorderPilot ProjectsPsychiatric Status Rating ScalesAccommodationCognitive therapyExposure-response preventionOCDPreschoolVery young children

Identifiers

PMID24657310
OpenAlexW2081387417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.