ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2014
Does electroencephalogram phase variability account for reduced P3 brain potential in externalizing disorders?
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuroimaging Insights into the Public Health Burden of Neuropsychiatric Disorders: A Systematic Review of Electroencephalography-Based Cognitive Biomarkers.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The role of single trial variability in event related potentials in children with attention deficit hyperactivity disorder.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Trial
- Clarifying the place of p300 in the empirical structure of psychopathology over development.Journal of psychopathology and clinical science · 2024Article
- Midfrontal theta reactivity to conflict and error are linked to externalizing and internalizing respectively.Personality neuroscience · 2024Article
- Parietal P3 and midfrontal theta prospectively predict the development of adolescent alcohol use.Psychological medicine · 2021Article
- Reduced premovement positivity during the stimulus-response interval precedes errors: Using single-trial and regression ERPs to understand performance deficits in ADHD.Psychophysiology · 2019Article
- Target-related parietal P3 and medial frontal theta index the genetic risk for problematic substance use.Psychophysiology · 2019Article
- Conflict-related medial frontal theta as an endophenotype for alcohol use disorder.Biological psychology · 2018Article
- Theta- and delta-band EEG network dynamics during a novelty oddball task.Psychophysiology · 2017Article
- What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude?International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
- A hierarchical causal taxonomy of psychopathology across the life span.Psychological bulletin · 2017Review
- Endophenotype best practices.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Review
- One-year developmental stability and covariance among oddball, novelty, go/no-go, and flanker event-related potentials in adolescence: A monozygotic twin study.Psychophysiology · 2016Article
- Neurofeedback Therapy for Enhancing Visual Attention: State-of-the-Art and Challenges.Frontiers in neuroscience · 2016Review
- Advances in Electrophysiological Research.Alcohol research : current reviews · 2015Review
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4 authors.
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Abstract
objectiveAmplitude deficits of the P3 event-related potential (ERP) are associated with externalizing psychopathology but little is known about the nature of underlying brain electrical activity that accounts for this amplitude reduction. We sought to understand if group differences in task-induced phase-locking in electroencephalographic (EEG) delta and theta frequencies may account for P3-externalizing associations.
methodsAdult males (N=410) completed a visual oddball task and frontal and parietal P3-related delta- and theta-band phase-invariant evoked energy and inter-trial phase-locking measures were investigated with respect to the externalizing spectrum, including substance dependence, adult antisociality, and childhood disruptive disorders. We hypothesized that P3-related phase-locking is weaker in externalizing-diagnosed individuals and this might mediate prior findings of reduced evoked P3 energy.
resultsReductions in both evoked energy and phase-locking, in both frequency bands, at both scalp sites, were associated with greater odds of externalizing diagnoses. Generally, adding phase-locking to evoked energy came with better prediction model fit. Moreover, reduced theta-band phase-locking partially mediated the effects of within-frequency evoked energy on externalizing prediction.
conclusionsInter-trial phase-locking underlying P3 appears to be an important distinction between externalizing and control subjects. SIGNIFICANCE: This cross-trial phase-variability for externalizing-diagnosed individuals might reflect deficient top-down "tuning" by neuromodulatory systems.
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