ReviewMedecine et maladies infectieuses2014
Propionibacterium acnes, an emerging pathogen: from acne to implant-infections, from phylotype to resistance.
Review in Medecine et maladies infectieuses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.Aesthetic plastic surgery · 2025Pooled it
- Evidence for infection in intervertebral disc degeneration: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Meta-analysis of the efficacy of preoperative skin preparation with alcoholic chlorhexidine compared to povidone iodine in orthopedic surgery.Scientific reports · 2021Pooled it
- Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical isolates from a hospital in Shanghai, China.Frontiers of medicine · 2016Trial
- In vitro emergence of amoxicillin-resistance and impact of amoxicillin on biofilm production across Cutibacterium acnes phylotypes?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Article
- Can antimicrobial peptides provide an improved antimicrobial strategy for treatment ofMicrobiology spectrum · 2025Article
- Cutibacterium acnes in lumbar spine, from skin to deep tissue. A colonization study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- From adhesion to destruction: minocycline's dual action against Cutibacterium acnes biofilms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Finegoldia magna infection after lumbar spine surgery determined based on targeted next-generation sequencing.BMC musculoskeletal disorders · 2025Article
- Intracellular infection of Cutibacterium acnes in macrophages of extensive peri-implantitis lesions: A clinical case series.Clinical implant dentistry and related research · 2024Article
- Review
- Increased biofilm formation in dual-strain compared to single-strain communities of Cutibacterium acnes.Scientific reports · 2024Article
- Comparative Genomic Analysis ofMicroorganisms · 2023Article
- Antimicrobial activity of thermophilin 110 against the opportunistic pathogen Cutibacterium acnes.Biotechnology letters · 2023Article
- The value of sonication on orthopaedic implants in an everyday clinical setting - an exploratory study.BMC musculoskeletal disorders · 2023Article
- Article
- Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.Nucleic acids research · 2023Article
- A microbiology study on the wounds of pediatric patients undergoing spinal fusion for scoliosis.Spine deformity · 2023Observational
- Antimicrobial Activity of Gelatin Nanofibers Enriched by Essential Oils againstNanomaterials (Basel, Switzerland) · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Propionibacterium acnes colonizes the lipid-rich sebaceous glands of the skin. This preferential anaerobic bacterium is easily identified if cultures are prolonged. It is involved in the inflammation process of acne, but until recently, it was neglected in other clinical presentations. Despite a reported low virulence, the new genomic, transcriptomic, and phylogenetic studies have allowed better understanding of this pathogen's importance that causes many chronic and recurrent infections, including orthopedic and cardiac prosthetic, and breast or eye implant-infections. These infections, facilitated by the ability of P. acnes to produce a biofilm, require using anti-biofilm active antibiotics such as rifampicin. The antibiogram of P. acnes is not systematically performed in microbiology laboratories because of its susceptibility to a wide range of antibiotics. However, in the last 10 years, the rate of antibiotic-resistant bacteria has increased, especially for macrolides and tetracyclines. Recently, rpoB gene mutations conferring resistance to rifampicin have been also reported. Thus in case of a biofilm growth mode, the therapeutic strategy should be discussed, according to the resistance phylotype and phenotype so as to optimize the treatment of these severe infections.
Indexed as
Identifiers
24656842What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.