ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2014
Social cognition in Alzheimer's disease: a separate construct contributing to dependence.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Spatial Dissociation of Atrophy and Hypophysiology in Alzheimer's Disease: Implications for Biomarkers.Human brain mapping · 2025Pooled it
- Article
- Age-Associated Behavioral Alterations in Laboratory-Housed Octodon degus.bioRxiv : the preprint server for biology · 2026Article
- Theory of Mind Deficits and Awareness in Alzheimer's Disease.Dementia and geriatric cognitive disorders · 2026Article
- Social cognition assessment in Chinese adults with mild cognitive impairment: a scoping review.Frontiers in public health · 2026Article
- Baseline facial emotion recognition is associated with clinical decline across the Alzheimer's disease spectrum: a multi-instrument longitudinal assessment study.Frontiers in aging neuroscience · 2026Article
- Factors Associated with the Social Behaviour of People with Alzheimer's Dementia: A Video Observation Study.Brain sciences · 2025Article
- The predictive value of social cognition assessment for 1-year follow-up functional outcomes in behavioral variant frontotemporal dementia.Journal of neurology · 2025Article
- Social Cognition in Neurodegenerative Disorders.Dementia and neurocognitive disorders · 2025Review
- Insulin-like Growth Factor 1 Impact on Alzheimer's Disease: Role in Inflammation, Stress, and Cognition.Current issues in molecular biology · 2025Review
- Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Future Therapeutic Strategies for Alzheimer's Disease: Focus on Behavioral and Psychological Symptoms.International journal of molecular sciences · 2024Review
- Facial emotion recognition is associated with executive functions and depression scores, but not staging of dementia, in mild-to-moderate Alzheimer's disease.Brain and behavior · 2024Article
- The importance of social behavior in nonhuman primate studies of aging: A mini-review.Neuroscience and biobehavioral reviews · 2023Review
- Moral Emotions and Their Brain Structural Correlates Across Neurodegenerative Disorders.Journal of Alzheimer's disease : JAD · 2023Article
- What Are the Neural Correlates of Impaired Awareness of Social Cognition and Function in Dementia? A Systematic Review.Brain sciences · 2022Review
- Retention and impairment of neurocognitive functions in mild cognitive impairment and Alzheimer's disease with a comprehensive neuropsychological test.Neuropsychopharmacology reports · 2022Article
- Cross-disorder and disorder-specific deficits in social functioning among schizophrenia and alzheimer's disease patients.PloS one · 2022Article
- Emotional Processing in Healthy Ageing, Mild Cognitive Impairment, and Alzheimer's Disease.International journal of environmental research and public health · 2021Article
- Social Cognition in Multiple Sclerosis: A 3-Year Follow-Up MRI and Behavioral Study.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
The extent to which social cognitive changes reflect a discrete constellation of symptoms dissociable from general cognitive changes in Alzheimer's disease (AD) is unclear. Moreover, whether social cognitive symptoms contribute to disease severity and progression is unknown. The current multicenter study investigated cross-sectional and longitudinal associations between social cognition measured with six items from the Blessed Dementia Rating Scale, general cognition, and dependence in 517 participants with probable AD. Participants were monitored every 6 months for 5.5 years. Results from multivariate latent growth curve models adjusted for sex, age, education, depression, and recruitment site revealed that social cognition and general cognition were unrelated cross-sectionally and throughout time. However, baseline levels of each were related independently to dependence, and change values of each were related independently to change in dependence. These findings highlight the separability of social and general cognition in AD. Results underscore the relevance of considering social cognition when modeling disease and estimating clinical outcomes related to patient disability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.