ArticleThe Journal of hospital infection2014
Evaluating the virucidal efficacy of hydrogen peroxide vapour.
Article in The Journal of hospital infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Could mouth rinses be an adjuvant in the treatment of SARS-CoV-2 patients? An appraisal with a systematic review.International journal of dental hygiene · 2022Pooled it
- A Systematic Review on the Efficacy of Vaporized Hydrogen Peroxide as a Non-Contact Decontamination System for Pathogens Associated with the Dental Environment.International journal of environmental research and public health · 2021Pooled it
- A systematic review of emerging human coronavirus (SARS-CoV-2) outbreak: focus on disinfection methods, environmental survival, and control and prevention strategies.Environmental science and pollution research international · 2021Pooled it
- Assessment of cleaning methods on bacterial burden of hospital privacy curtains: a pilot randomized controlled trial.Scientific reports · 2021Trial
- Exploring novel kinetics of automated HMicrobiology spectrum · 2026Article
- In vitro virucidal activity of chemical compounds against porcine transmissible gastroenteritis virus and porcine respiratory coronavirus.BMC veterinary research · 2025Article
- Process Technologies for Disinfection of Food-Contact Surfaces in the Dry Food Industry: A Review.Microorganisms · 2025Review
- Antiviral activity of contact lens care solutions and rub-and-rinse regimen against adenovirus.Optometry and vision science : official publication of the American Academy of Optometry · 2025Article
- Physicochemical methods for disinfection of contaminated surfaces - a way to control infectious diseases.Journal of environmental health science & engineering · 2024Review
- Use of Hydrogen Peroxide Vapour for Microbiological Disinfection in Hospital Environments: A Review.Bioengineering (Basel, Switzerland) · 2024Review
- A systematic overview of metal nanoparticles as alternative disinfectants for emerging SARS-CoV-2 variants.Archives of microbiology · 2024Review
- A comprehensive literature scoping review of infection prevention and control methods for viral-mediated gene therapies.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Eco-evolutionary dynamics of experimentalMicrobiology (Reading, England) · 2023Article
- Article
- Manipulation of Oxidative Stress Responses by Non-Thermal Plasma to Treat Herpes Simplex Virus Type 1 Infection and Disease.International journal of molecular sciences · 2023Review
- The in situ efficacy of whole room disinfection devices: a literature review with practical recommendations for implementation.Antimicrobial resistance and infection control · 2022Review
- Article
- Disinfectants against SARS-CoV-2: A Review.Viruses · 2022Review
- Management of SARS-CoV-2 Transmission in Emergency Dental Settings: Current Knowledge and Personal Experience.Disaster medicine and public health preparedness · 2022Article
- Virucidal Activity of Over-the-Counter Oral Care Products Against SARS-CoV-2.Oral health & preventive dentistry · 2022Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents.
aimTo evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV).
methodsThe viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m(3) environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL.
findingsNo viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes.
conclusionHPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.