Evidence map›Paper›PMID 24655474›Full record

ArticleEmerging infectious diseases2014

Large outbreak of Cryptosporidium hominis infection transmitted through the public water supply, Sweden.

Micael Widerström, Caroline Schönning, Mikael Lilja, Marianne Lebbad, Thomas Ljung, Görel Allestam, Martin Ferm, Britta Björkholm, Anette Hansen, Jari Hiltula and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 177 citations in OpenAlex.

  1. Prevalence of Cryptosporidium spp. in water: a global systematic review and meta-analysis.Environmental science and pollution research international · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. Advancing genomics for waterborne pathogen surveillance in Australia.The Lancet regional health. Western Pacific · 2026
    Review
  5. From rare to recognized: enhanced detection uncoversEmerging microbes & infections · 2025
    Article
  6. Review
  7. Article
  8. ConcurrentEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  9. Article
  10. Retrospective case-case study investigation of a significant increase inEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  11. Article
  12. Review
  13. Emerging microbes & infections · 2024
    Article
  14. Outbreak of the novelEpidemiology and infection · 2024
    Article
  15. Review
  16. Nanoparticle Lysis ofMethods and protocols · 2024
    Article
  17. Article
  18. Article
  19. Biopreserving Pathogens: Promise & Peril.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2024
    Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Micael Widerström
Caroline Schönning
Mikael Lilja
Marianne Lebbad
Thomas Ljung
Görel Allestam
Martin Ferm
Britta Björkholm
Anette Hansen
Jari Hiltula
Jonas Långmark
Margareta Löfdahl
Maria Omberg
Christina Reuterwall
Eva Samuelsson
Katarina Widgren
Anders Wallensten
Johan Lindh
Umeå University · SEÖstersunds Hospital · SEPublic Health Agency of Sweden · SEMid Sweden University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In November 2010, ≈27,000 (≈45%) inhabitants of Östersund, Sweden, were affected by a waterborne outbreak of cryptosporidiosis. The outbreak was characterized by a rapid onset and high attack rate, especially among young and middle-aged persons. Young age, number of infected family members, amount of water consumed daily, and gluten intolerance were identified as risk factors for acquiring cryptosporidiosis. Also, chronic intestinal disease and young age were significantly associated with prolonged diarrhea. Identification of Cryptosporidium hominis subtype IbA10G2 in human and environmental samples and consistently low numbers of oocysts in drinking water confirmed insufficient reduction of parasites by the municipal water treatment plant. The current outbreak shows that use of inadequate microbial barriers at water treatment plants can have serious consequences for public health. This risk can be minimized by optimizing control of raw water quality and employing multiple barriers that remove or inactivate all groups of pathogens.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCryptosporidiosisCryptosporidiumDisease OutbreaksFemaleHumansInfantInfant, NewbornMaleMiddle AgedSwedenWatercryptosporidiosis/epidemiologycryptosporidiosis/prevention and controlcryptosporidiosis/transmissionCryptosporidium hominis infectiondiarrheadisease outbreaksdrinking watermolecular typingquestionnairesrisk factorswaste management, parasiteswaterborne infectionswater microbiologywater supply

Identifiers

PMID24655474
PMCPMC3966397
OpenAlexW2097475192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.