ArticleBMC infectious diseases2014
Threat of drug resistant Staphylococcus aureus to health in Nepal.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 92 citations in OpenAlex.
- Prevalence, Antimicrobial Resistance Profile, and Multidrug Resistance of Methicillin-ResistantHealth science reports · 2026Article
- Nasal Carriage Rate of Biofilm Producing Methicillin Resistant Staphylococcus aureus and Its Associated Factors Among Health Care Workers at Hospital of Central Ethiopia.MicrobiologyOpen · 2026Article
- Prevalence and associated risk factors of Staphylococcus aureus nasal colonization among a cohort of immunocompromised individuals in Lagos, Nigeria.BMC infectious diseases · 2025Article
- Bloodstream infections: trends in etiology and antimicrobial resistance in 10 years in Eastern Nepal.BMC infectious diseases · 2025Article
- Biofilm formation, methicillin resistance and SCCmec types among Staphylococcus aureus isolated from clinical samples from a tertiary care hospital, in Nepal.BMC infectious diseases · 2025Article
- Characterization and complete genome sequence of highly lytic phage active against methicillin-resistant Staphylococcus aureus (MRSA) isolated from Egypt.Virology journal · 2024Article
- Integrating multi-wet laboratory diagnostics to study staphylococci in animals in Uganda.BMC microbiology · 2024Article
- Article
- Detection of Biofilm Production and Antibiotic Susceptibility Pattern among Clinically IsolatedJournal of pathogens · 2024Article
- Antimicrobial Resistance and Biofilm Formation ofPolish journal of microbiology · 2023Article
- Prevalence, antimicrobial susceptibility pattern and multidrug resistance of methicillin-resistantBMJ open · 2023Observational
- Biofilm forming multidrug resistantIranian journal of veterinary research · 2023Article
- Nasal Carriage Rate ofInfection and drug resistance · 2023Article
- Phenotypic detection of methicillin resistance, biofilm production, and inducible clindamycin resistance in Staphylococcus aureus clinical isolates in Kathmandu, Nepal.Tropical medicine and health · 2022Article
- High level of persister frequency in clinical staphylococcal isolates.BMC microbiology · 2022Article
- Staphylococcus aureus with inducible clindamycin resistance and methicillin resistance in a tertiary hospital in Nepal.Tropical medicine and health · 2021Article
- Inducible Clindamycin Resistance and Biofilm Production among Staphylococci Isolated from Tertiary Care Hospitals in Nepal.Infectious disease reports · 2021Article
- Inducible Clindamycin Resistant Staphylococcus aureus among Patients Attending Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2021Article
- Antibiotic Susceptibility, Biofilm Production, and Detection ofDiseases (Basel, Switzerland) · 2021Article
- Non-Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus is the most commonly isolated organism from the different clinical samples in hospital. The emergence and dissemination of methicillin resistant Staphylococcus aureus (MRSA) and growing resistance to non-beta-lactam antibiotics is making treatment of infections due to this organism increasingly difficult.
methodsThis study was conducted to determine the frequency of Staphylococcus aureus isolated from different clinical samples, rates of MRSA and full antibiotic susceptibility profiles. Clinical samples were cultured and Staphylococcus aureus was identified using standard microbiological methods recommended by the American Society for Microbiology (ASM). Methicillin resistance was confirmed using cefoxitin and oxacillin disks. Inducible clindamycin resistance was identified using D-zone test.
resultsFrom the processed samples, 306 isolates of Staphylococcus aureus were recovered. All the isolates were susceptible to vancomycin and teicoplanin. Methicillin resistance was observed in 43.1% of isolates while inducible clindamycin resistance in 12.4% of the isolates.
conclusionsThe results of our study reveals that rates of resistance to commonly prescribed antibiotics in Staphylococcus aureus clinical isolates is high. In particular, rate of methicillin resistance is alarming, prompting concern on the rational use of antibiotics and vigilant laboratory-based surveillance of resistance rates in Nepal.
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