ReviewAnnual review of immunology2014
Systems-level analysis of innate immunity.
Review in Annual review of immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Systems-Level Analysis of HPAI H5N1 Infection in Ducks: Integrating Transcriptomic, Proteomic, and Phosphoproteomic Data.International journal of molecular sciences · 2026Article
- Challenges in the standardization of innate immune status assessment.Frontiers in immunology · 2026Review
- Protein swarm-based cause-effect analysis: effects of microRNAs on cooperation networks linking COVID-19 infections, atherosclerosis, and Alzheimer's disease.Frontiers in cardiovascular medicine · 2025Article
- Proteomics Analysis of Duck Lung Tissues in Response to Highly Pathogenic Avian Influenza Virus.Microorganisms · 2024Article
- Proteomics: Unraveling the Cross Talk Between Innate Immunity and Disease Pathophysiology, Diagnostics, and Treatment Options.Advances in experimental medicine and biology · 2024Review
- Proteomic analysis of differential expression of lung proteins in response to highly pathogenic avian influenza virus infection in chickens.Archives of virology · 2022Article
- Profiling the immune response toVirulence · 2021Article
- NFAT5 Amplifies Antipathogen Responses by Enhancing Chromatin Accessibility, H3K27 Demethylation, and Transcription Factor Recruitment.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Elucidating host-microbe interactions in vivo by studying population dynamics using neutral genetic tags.Immunology · 2021Review
- Discrimination and systemic inflammation: A critical review and synthesis.Brain, behavior, and immunity · 2020Review
- Immunosenescence is both functional/adaptive and dysfunctional/maladaptive.Seminars in immunopathology · 2020Review
- The Whole Body as the System in Systems Immunology.iScience · 2020Review
- Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives.Journal of molecular biology · 2020Review
- PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Macrophages employ quorum licensing to regulate collective activation.Nature communications · 2020Article
- Immune promotive effect of bioactive peptides may be mediated by regulating the expression of SOCS1/miR-155.Experimental and therapeutic medicine · 2019Article
- Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine.Nature communications · 2019Article
- Immunomodulatory Effects and Induction of Apoptosis by Different Molecular Weight Chitosan Oligosaccharides in Head Kidney Macrophages From Blunt Snout Bream (Frontiers in immunology · 2019Article
- Metabolomics in Plant Priming Research: The Way Forward?International journal of molecular sciences · 2018Review
- System immunology-based identification of blood transcriptional modules correlating to antibody responses in sheep.NPJ vaccines · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Systems-level analysis of biological processes strives to comprehensively and quantitatively evaluate the interactions between the relevant molecular components over time, thereby enabling development of models that can be employed to ultimately predict behavior. Rapid development in measurement technologies (omics), when combined with the accessible nature of the cellular constituents themselves, is allowing the field of innate immunity to take significant strides toward this lofty goal. In this review, we survey exciting results derived from systems biology analyses of the immune system, ranging from gene regulatory networks to influenza pathogenesis and systems vaccinology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.