ReviewAnnals of the New York Academy of Sciences2014
Dissecting impulsivity and its relationships to drug addictions.
Review in Annals of the New York Academy of Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
147 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Etiologic, Theory-Based, Ontogenetic Hierarchical Framework of Alcohol Use Disorder: A Translational Systematic Review of Reviews.Psychological bulletin · 2021Pooled it
- Neuroimaging Impaired Response Inhibition and Salience Attribution in Human Drug Addiction: A Systematic Review.Neuron · 2018Pooled it
- Alcohol-induced changes in mesostriatal resting-state functional connectivity are linked to sensation seeking in young adults.Alcohol, clinical & experimental research · 2023Trial
- Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Impulse Inhibition in Abstinent Patients With Methamphetamine Addiction: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Trait self-control predicts drinking patterns during treatment for alcohol use disorder and recovery up to three years following treatment.Addictive behaviors · 2019Trial
- Relationships between generalized impulsivity and subjective stimulant and sedative responses following alcohol administration.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019Trial
- Associations Between Behavioral and Neural Correlates of Inhibitory Control and Amphetamine Reward Sensitivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Trial
- Aripiprazole Suppression of Drinking in a Clinical Laboratory Paradigm: Influence of Impulsivity and Self-Control.Alcoholism, clinical and experimental research · 2017Trial
- Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health.Molecular psychiatry · 2026Article
- Self-Deception in Addiction Rehabilitation: Impulsivity and Self-Efficacy as Predictors of Manipulation and Mystification.Behavioral sciences (Basel, Switzerland) · 2026Article
- Learning Mechanisms in Alcohol Use Disorders.Addiction biology · 2026Review
- Amphetamine in adolescence induces a sex-specific mesolimbic dopamine phenotype in the adult prefrontal cortex.Communications biology · 2025Article
- The mesocorticolimbic system in stimulant use disorder.Molecular psychiatry · 2025Review
- Divergent outcomes of delta 9 - tetrahydrocannabinol (THC) in adolescence on mesocortical dopamine and cognitive development in male and female mice.Psychopharmacology · 2025Article
- Temperament, brain structure and problematic video gaming in adolescence - A six-year longitudinal study.Journal of behavioral addictions · 2025Article
- Effects of methamphetamine on delay discounting in rats using concurrent chains.Learning & behavior · 2025Review
- Article
- Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review.Addiction neuroscience · 2025Article
- How Do Common Marmosets Maintain the Balance Between Response Execution and Action Inhibition?American journal of primatology · 2025Article
- Aberrant glutamatergic systems underlying impulsive behaviors: Insights from clinical and preclinical research.Progress in neuro-psychopharmacology & biological psychiatry · 2024Review
87 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Addictions are often characterized as forms of impulsive behavior. That said, it is often noted that impulsivity is a multidimensional construct, spanning several psychological domains. This review describes the relationship between varieties of impulsivity and addiction-related behaviors, the nature of the causal relationship between the two, and the underlying neurobiological mechanisms that promote impulsive behaviors. We conclude that the available data strongly support the notion that impulsivity is both a risk factor for, and a consequence of, drug and alcohol consumption. While the evidence indicating that subtypes of impulsive behavior are uniquely informative--either biologically or with respect to their relationships to addictions--is convincing, multiple lines of study link distinct subtypes of impulsivity to low dopamine D2 receptor function and perturbed serotonergic transmission, revealing shared mechanisms between the subtypes. Therefore, a common biological framework involving monoaminergic transmitters in key frontostriatal circuits may link multiple forms of impulsivity to drug self-administration and addiction-related behaviors. Further dissection of these relationships is needed before the next phase of genetic and genomic discovery will be able to reveal the biological sources of the vulnerability for addiction indexed by impulsivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.