ArticleBacteriophage2014
Different approaches for using bacteriophages against antibiotic-resistant bacteria.
Article in Bacteriophage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Recent trends in the use of bacteriophages as replacement of antimicrobials against food-animal pathogens.Frontiers in veterinary science · 2023Review
- Phage Therapy: A Different Approach to Fight Bacterial Infections.Biologics : targets & therapy · 2022Review
- Computational prediction of inter-species relationships through omics data analysis and machine learning.BMC bioinformatics · 2018Article
- Article
- A need for careful consideration of bacteriophage therapy.The Indian journal of medical research · 2016Article
- Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- T4-like coliphage ΦKAZ14 virulent to pathogenic and extended spectrum β-lactamase-producing Escherichia coli of poultry origin.Virologica Sinica · 2015Article
- Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Natural solution to antibiotic resistance: bacteriophages 'The Living Drugs'.World journal of microbiology & biotechnology · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial resistance to antibiotics is an emerging threat requiring urgent solutions. Ever since their discovery, lytic bacteriophages have been suggested as therapeutic agents, but their application faces various obstacles: sequestration of the phage by the spleen and liver, antibodies against the phage, narrow host range, poor accessibility to the infected tissue, and bacterial resistance. Variations on bacteriophage use have been suggested, such as temperate phages as gene-delivery vehicles into pathogens. This approach, which is proposed to sensitize pathogens residing on hospital surfaces and medical personnel's skin, and its prospects are described in this addendum. Furthermore, phage-encoded products have been proposed as weapons against antibiotic resistance in bacteria. We describe a new phage protein which was identified during basic research into T7 bacteriophages. This protein may serendipitously prove useful for treating antibiotic-resistant pathogens. We believe that further basic research will lead to novel strategies in the fight against antibiotic-resistant bacteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.