ArticleBacteriophage2014
Molecular imaging of T4 phage in mammalian tissues and cells.
Article in Bacteriophage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Mechanistic insights into phage dynamics to overcome intracellular bacterial reservoirs in urinary tract infections.Npj viruses · 2026Article
- When bacteriophages encounter macrophages during their journey through the human body.Frontiers in cellular and infection microbiology · 2026Review
- Article
- Antibiotic-resistant Acinetobacter baumannii can be killed by a combination of bacteriophages and complement.Medical microbiology and immunology · 2025Article
- Pharmacodynamic Evaluation of Phage Therapy in Ameliorating ETEC-Induced Diarrhea in Mice Models.Microorganisms · 2024Article
- Liver sinusoidal cells eliminate blood-borne phage K1F.mSphere · 2024Article
- Review
- The Novel Role of Phage Particles in Chronic Liver Diseases.Microorganisms · 2023Review
- Recent trends in the use of bacteriophages as replacement of antimicrobials against food-animal pathogens.Frontiers in veterinary science · 2023Review
- Bacteriophages as Biocontrol Agents in Livestock Food Production.Microorganisms · 2022Review
- Article
- Bacteriophage and the Innate Immune System: Access and Signaling.Microorganisms · 2019Review
- Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection.Science (New York, N.Y.) · 2019Article
- Phage therapy as a renewed therapeutic approach to mycobacterial infections: a comprehensive review.Infection and drug resistance · 2019Article
- Advantages and Limitations of Bacteriophages for the Treatment of Bacterial Infections.Frontiers in pharmacology · 2019Review
- Biodistribution of Liposome-Encapsulated Bacteriophages and Their Transcytosis During Oral Phage Therapy.Frontiers in microbiology · 2019Article
- Engineered K1F bacteriophages kill intracellular Escherichia coli K1 in human epithelial cells.Scientific reports · 2018Article
- Effects ofViruses · 2018Article
- Characterization of the bacteriophages binding to human matrix molecules.International journal of biological macromolecules · 2018Article
- Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics.Viruses · 2017Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in phage therapy encourage scientific interest in interactions of phages with human and animal organisms. This has created a need for developing tools that facilitate studies of phage circulation and deposition in tissues and cells. Here we propose a new green fluorescent protein (GFP)-based method for T4 phage molecular imaging in living systems. The method employs decoration of a phage capsid with GFP fused to the N-terminus of Hoc protein by in vivo phage display. Fluorescent phages were positively assessed as regards their applicability for detection inside living mammalian cells (by phagocytosis) and tissues (filtering and retention by lymph nodes and spleen). Molecular imaging provides innovative techniques that have brought substantial progress in life sciences. We propose it as a useful tool for studies of phage biology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.