ReviewJournal of medicine and life2014
Brief history of syphilis.
Review in Journal of medicine and life, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurosyphilis-Induced Psychosis in Europe: A Systematic Review of Case Reports.Pathogens (Basel, Switzerland) · 2024Pooled it
- Advancements in Syphilis Vaccine Development.Sexually transmitted diseases · 2026Article
- Severe Early Congenital Syphilis with Multiorgan Involvement in a Preterm Neonate: A Case Report.Reports (MDPI) · 2026Article
- Review
- Human placental trophoblasts support sustainedbioRxiv : the preprint server for biology · 2026Article
- Temporal shifts in polygenic traits track major epidemics in Western Eurasia.bioRxiv : the preprint server for biology · 2026Article
- A fresh look at varicella vaccination.Human vaccines & immunotherapeutics · 2025Review
- Remarkable spine erosion in cardiovascular syphilis - Computed tomography reconstruction of a century-old forensic case.Forensic science, medicine, and pathology · 2025Article
- Clinical features in four patients with syphilitic outer retinopathy.Japanese journal of ophthalmology · 2025Article
- The Clinical Spectrum and Outcomes of Ocular Syphilis in Saudi Arabia: The Emergence of a Uveitic Masquerader.Journal of epidemiology and global health · 2025Article
- Editorial for the Special Issue "Infectious and Tropical Diseases: Symptoms, Diagnosis and Treatment".Medicina (Kaunas, Lithuania) · 2025Article
- The Rise of Syphilis Infections and Reinfections over a Decade (2009-2019) in the Bolognese Area: A Retrospective Analysis.Microorganisms · 2025Article
- Decoding and Unravelling Mpox, Herpes, and Syphilis Infections: A State of Art Review.Current pharmaceutical biotechnology · 2025Review
- Oral lesions as the presenting manifestation of syphilis: A case series of an alarming trend in Kuwait.IDCases · 2025Article
- Ocular vs neurosyphilis. are they the same? A guide to investigation and management.Eye (London, England) · 2024Review
- Metagenomic and paleopathological analyses of a historic documented collection explore ancient dental calculus as a diagnostic tool.Scientific reports · 2024Article
- The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges.Acta dermato-venereologica · 2024Review
- Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024Article
- Global, regional, and national burden of syphilis, 1990-2021 and predictions by Bayesian age-period-cohort analysis: a systematic analysis for the global burden of disease study 2021.Frontiers in medicine · 2024Article
- Acute vision changes as the presenting symptom of ocular syphilis - A case series of two.IDCases · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Before the discovery of Treponema pallidum as the etiologic agent, the origins of syphilis have been the subject of several debates. Diverse therapeutic agents were employed in an attempt to cure the disease. Examining the milestones in the history of syphilis, the present article reviews the existing theories that tried to explain the origins of the disease, the approach in art, the cultural and the evolution of the treatments from the empiric means to the discovery of penicillin.
Indexed as
Identifiers
24653750PMC3956094What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.