Evidence map›Paper›PMID 24653724›Full record

ReviewFrontiers in immunology2014

MicroRNAs, Major Players in B Cells Homeostasis and Function.

Richard Danger, Faouzi Braza, Magali Giral, Jean-Paul Soulillou, Sophie Brouard

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
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  4. Innate and adaptive immune evasion by dengue virus.Frontiers in cellular and infection microbiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard DangerInstitute of Liver Studies, Medical Research Council Centre for Transplantation, King's College Hospital, King's College London , London , UK ; Institut National de la Santé et de la Recherche Médicale, U1064, Institut de Transplantation Urologie Néphrologie , Nantes , France ; Faculté de Médecine, Université de Nantes , Nantes , France.
Faouzi BrazaInstitut National de la Santé et de la Recherche Médicale, U1064, Institut de Transplantation Urologie Néphrologie , Nantes , France ; Faculté de Médecine, Université de Nantes , Nantes , France.
Magali GiralInstitut National de la Santé et de la Recherche Médicale, U1064, Institut de Transplantation Urologie Néphrologie , Nantes , France ; Faculté de Médecine, Université de Nantes , Nantes , France ; Centre Hospitalier Universitaire, Hôtel Dieu , Nantes , France.
Jean-Paul SoulillouInstitut National de la Santé et de la Recherche Médicale, U1064, Institut de Transplantation Urologie Néphrologie , Nantes , France ; Faculté de Médecine, Université de Nantes , Nantes , France ; Centre Hospitalier Universitaire, Hôtel Dieu , Nantes , France.
Sophie BrouardInstitut National de la Santé et de la Recherche Médicale, U1064, Institut de Transplantation Urologie Néphrologie , Nantes , France ; Faculté de Médecine, Université de Nantes , Nantes , France ; Centre Hospitalier Universitaire, Hôtel Dieu , Nantes , France.

Funding

Medical Research Council MR/J006742/1
6 · The paper itself

Abstract

As a main actor in humoral immunity, B cells participate in various antibody-related disorders. However, a deeper understanding of B-cell differentiation and function is needed in order to decipher their immune-modulatory roles, notably with the recent highlighting of regulatory B cells. microRNAs (miRNAs), key factors in various biological and pathological processes, have been shown to be essential for B-cell homeostasis, and therefore understanding their participation in B-cell biology could help identify biomarkers and contribute toward curing B-cell-related immune disorders. This review aims to report studies casting light on the roles played by miRNAs in B-cell lineage and function and B-cell-related immune pathologies.

Indexed as

B cellgene-expression regulationimmune disorderimmunologymicroRNA

Identifiers

PMID24653724
PMCPMC3949129

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.