ArticleFrontiers in neural circuits2014
Spatial pattern of intra-laminar connectivity in supragranular mouse auditory cortex.
Article in Frontiers in neural circuits, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Patchy harmonic functional connectivity of the mouse auditory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A Novel Layer 4 Corticofugal Cell Type/Projection Involved in Thalamo-Cortico-Striatal Sensory Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Altered Response Dynamics and Increased Population Correlation to Tonal Stimuli Embedded in Noise in Aging Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
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- Automatic detection of adult cardiomyocyte for high throughput measurements of calcium and contractility.PloS one · 2021Article
- Propagating wave activity in a tangential cortical slice.Neuroreport · 2020Article
- Article
- Thalamocortical and Intracortical Inputs Differentiate Layer-Specific Mouse Auditory Corticocollicular Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Neuronal Avalanches in Input and Associative Layers of Auditory Cortex.Frontiers in systems neuroscience · 2019Article
- Extracting neuronal functional network dynamics via adaptive Granger causality analysis.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Article
- Sublaminar Subdivision of Mouse Auditory Cortex Layer 2/3 Based on Functional Translaminar Connections.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Large-scale functional network overlap is a general property of brain functional organization: Reconciling inconsistent fMRI findings from general-linear-model-based analyses.Neuroscience and biobehavioral reviews · 2016Review
- Immediate manifestation of acoustic trauma in the auditory cortex is layer specific and cell type dependent.Journal of neurophysiology · 2016Article
- Mapping Auditory Synaptic Circuits with Photostimulation of Caged Glutamate.Methods in molecular biology (Clifton, N.J.) · 2016Article
- Ncm, a Photolabile Group for Preparation of Caged Molecules: Synthesis and Biological Application.PloS one · 2016Article
- Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci.Nature communications · 2015Article
- Spatial organization of excitatory synaptic inputs to layer 4 neurons in mouse primary auditory cortex.Frontiers in neural circuits · 2015Article
- Towards a "canonical" agranular cortical microcircuit.Frontiers in neuroanatomy · 2014Article
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3 authors at 1 institution in 1 country.
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Abstract
Neuronal responses and topographic organization of feature selectivity in the cerebral cortex are shaped by ascending inputs and by intracortical connectivity. The mammalian primary auditory cortex has a tonotopic arrangement at large spatial scales (greater than 300 microns). This large-scale architecture breaks down in supragranular layers at smaller scales (around 300 microns), where nearby frequency and sound level tuning properties can be quite heterogeneous. Since layer 4 has a more homogeneous architecture, the heterogeneity in supragranular layers might be caused by heterogeneous ascending input or via heterogeneous intralaminar connections. Here we measure the functional 2-dimensional spatial connectivity pattern of the supragranular auditory cortex on micro-column scales. In general connection probability decreases with radial distance from each neuron, but the decrease is steeper in the isofrequency axis leading to an anisotropic distribution of connection probability with respect to the tonotopic axis. In addition to this radial decrease in connection probability we find a patchy organization of inhibitory and excitatory synaptic inputs that is also anisotropic with respect to the tonotopic axis. These periodicities are at spatial scales of ~100 and ~300 μm. While these spatial periodicities show anisotropy in auditory cortex, they are isotropic in visual cortex, indicating region specific differences in intralaminar connections. Together our results show that layer 2/3 neurons in auditory cortex show specific spatial intralaminar connectivity despite the overtly heterogeneous tuning properties.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.