ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2014
Aberration of the Wnt signaling pathway in pulmonary fatal adenocarcinoma: a case report.
Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Low-Grade Fetal Adenocarcinoma of the Lung onClinical case reports · 2025Article
- Novel genetic characteristics in low-grade fetal adenocarcinoma of the lung.Thoracic cancer · 2021Article
- Well-differentiated fetal adenocarcinoma of the lung: clinicopathologic features of 45 cases in China.International journal of clinical and experimental pathology · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
We report a case of a 58-year-old woman showed a homogeneous well-defined perihilar mass in the right upper lobe and fully surrounded by aerated parenchyma at computed tomography (CT). A right upper lobectomy with mediastinal lymph node sampling was performed. A pathologic diagnosis of well-differentiated fetal adenocarcinoma of the lung was made and staged as T2bN0M0. For the expression of Wnt signaling pathway molecules, positive expressions of Wnt1, β-catenin, c-Myc, Cyclin D1and MMP7 were especially prominent in budding solid nests, but not in glandular structures. The nuclear/cytoplasmic localization of β-catenin accompanied upregulation of Wnt signaling pathway molecules in budding solid nests. These results demonstrated that elevated nuclear/cytoplasmic expression of β-catenin in fatal adenocarcinoma might be regulated by the Wnt signaling pathway.
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Registered trials
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