Evidence map›Paper›PMID 24653559›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2014

Preliminary examination of herbal extracts on the inhibition of Helicobacter pylori.

Gulcihan Guzeldag, Lutfiye Kadioglu, Aysun Mercimek, Fatih Matyar

Open access · diamondAbstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Anti-Life (Basel, Switzerland) · 2023
    Article
  4. Effectiveness ofEvidence-based complementary and alternative medicine : eCAM · 2017
    Review
  5. Chemistry and Pharmacology of Citrus sinensis.Molecules (Basel, Switzerland) · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gulcihan GuzeldagFaculty of Arts and Sciences, Department of Molecular Biology and Genetics, Kilis 7 Aralik University, 79000, Kilis, Turkey.
Lutfiye KadiogluFaculty of Arts and Sciences, Department of Molecular Biology and Genetics, Kilis 7 Aralik University, 79000, Kilis, Turkey.
Aysun MercimekFaculty of Arts and Sciences, Department of Molecular Biology and Genetics, Kilis 7 Aralik University, 79000, Kilis, Turkey.
Fatih MatyarFaculty of Education, Department of Science and Technology Education, Cukurova University, 01330 Saricam, Adana, Turkey.
Cukurova University · TRKilis 7 Aralık University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis work aims at describing the traditional uses, to determine the antimicrobial potential of two different extracts hexane, acetone of the leaves of Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, Citrus paradisi on clinical strain of H. pylori in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. H. pylori strain was a culture collection of Hacettepe University, Turkey.

methodsThe activity was quantitatively assessed on the basis of the inhibition zone, and their activity index was also calculated along with the MIC method.

resultsAll the plants demonstrated antimicrobial activity against H. pylori with zone of inhibition diameters ranging from 0 - 30 mm and minimum inhibitory concentration (MIC) values ranging from 1:512-1:4096 dilutions.

conclusionThe results may serve as scientific validation of the ethnomedicinal uses of the Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, and Citrus paradisi in the treatment of H. pylori-related infections. However, further investigations would be necessary to determine their toxicological properties, in-vivo potencies and mechanism of action against H. pylori.

Indexed as

CitrusLaurusAnti-Bacterial AgentsHelicobacter InfectionsHelicobacter pyloriMicrobial Sensitivity TestsPlant ExtractsAnti-Bacterial AgentsPlant Extractsacetoneantimicrobial activityHelicobacter pylorihexaneMICplant extracts

Identifiers

PMID24653559
PMCPMC3957247
OpenAlexW2091848398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.