ArticleBlood2014
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis.
Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Monitoring Neurocognitive Functioning After Pediatric Cellular Therapy or Hematopoietic Cell Transplant: Guidelines From the COG Neurocognition in Cellular Therapies Task Force.Transplantation and cellular therapy · 2022Guideline
- Cerebrospinal fluid profile associated with the incidence and outcomes of patients with chronic graft-versus-host disease after haploidentical hematopoietic stem cell transplantation.Blood science (Baltimore, Md.) · 2025Article
- Article
- Toward a Better Understanding of the Atypical Features of Chronic Graft-Versus-Host Disease: A Report from the 2020 National Institutes of Health Consensus Project Task Force.Transplantation and cellular therapy · 2022Review
- Article
- National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report.Transplantation and cellular therapy · 2021Article
- Noninvasive tools based on immune biomarkers for the diagnosis of central nervous system graft-World journal of clinical cases · 2021Article
- Acute Graft-Frontiers in immunology · 2021Review
- A Case Report of Central Nervous System Graft-Versus-Host Disease and Literature Review.Frontiers in neurology · 2021Article
- Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia.The Journal of clinical investigation · 2020Article
- Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation.Nature communications · 2018Article
- CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.The Journal of clinical investigation · 2018Article
- Central nervous system graft-versus-host disease (CNS-GvHD) after allogeneic haematopoietic stem cell transplantation.BMJ case reports · 2018Article
- Case report: Central nervous system involvement of human graft versus host disease: Report of 7 cases and a review of literature.Medicine · 2017Article
- Host interleukin 6 production regulates inflammation but not tryptophan metabolism in the brain during murine GVHD.JCI insight · 2017Article
- Chronic Graft-versus-host Disease Presenting with Multiple Punctate Intracranial Lesions on Contrast-enhanced Magnetic Resonance Imaging.Internal medicine (Tokyo, Japan) · 2017Article
- Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.Transplantation · 2016Article
- Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells.Blood · 2016Article
- Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.Science translational medicine · 2015Article
- Successful treatment of meningeal graft-versus-host disease in a haematopoietic stem cell transplant recipient.International journal of hematology · 2015Article
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Authors and funding
16 authors at 7 institutions in 1 country.
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.