ReviewClinical cardiology2014
Fractional flow reserve: an updated review.
Review in Clinical cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Intravascular Ultrasound Imaging-Guided Versus Coronary Angiography-Guided Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2020Pooled it
- Outcomes associated with fractional flow-guided revascularization: a meta-analysis.Clinical cardiology · 2014Pooled it
- Digital twins and digital models of the human circulatory system.Nature reviews bioengineering · 2026Article
- Uncertainty Quantification and Sensitivity Analysis for Non-invasive Model-Based Instantaneous Wave-Free Ratio Prediction.International journal for numerical methods in biomedical engineering · 2025Article
- Accuracy of analytically determined fractional flow reserve derived from coronary angiography for non-invasive assessment of coronary artery stenosis.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Is it the Time to Move Towards Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve Guided Percutaneous Coronary Intervention? The Pros and Cons.Current cardiology reviews · 2023Review
- A CT-FFR-guided unroofing procedure for repairing the anomalous origin of the left coronary artery-a case report.Frontiers in cardiovascular medicine · 2023Article
- Fractional Flow Reserve-Guided Coronary Revascularization: Evidence from Randomized and Non-Randomized Studies.Diagnostics (Basel, Switzerland) · 2022Review
- Myocardial bridge evaluation towards personalized medicine: study design and preliminary results of the RIALTO registry.European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- Impact of coronary plaque morphology on the precision of computational fractional flow reserve derived from optical coherence tomography imaging.Cardiovascular diagnosis and therapy · 2022Article
- Comprehensive functional and anatomic assessment of myocardial bridging: Unlocking the Gordian Knot.Frontiers in cardiovascular medicine · 2022Review
- Comparison of automated beam hardening correction (ABHC) algorithms for myocardial perfusion imaging using computed tomography.Medical physics · 2021Article
- Value of Delta Fractional Flow Reserve (ΔFFR) For Predicting Coronary Ischemic Lesions.Galen medical journal · 2020Article
- Calibration-free beam hardening correction for myocardial perfusion imaging using CT.Medical physics · 2019Article
- A new CFD based non-invasive method for functional diagnosis of coronary stenosis.Biomedical engineering online · 2018Article
- Reasons and implications of agreements and disagreements between coronary flow reserve, fractional flow reserve, and myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Review
- Preliminary Report on the Safety and Efficacy of Staged versus Complete Revascularization in Patients with Multivessel Disease at the Time of Primary Percutaneous Coronary Intervention.The International journal of angiology : official publication of the International College of Angiology, Inc · 2017Article
- Improvement of Subjective Well-Being by Ranolazine in Patients with Chronic Angina and Known Myocardial Ischemia (IMWELL Study).Cardiology and therapy · 2017Article
- Experimental and early investigational drugs for angina pectoris.Expert opinion on investigational drugs · 2016Review
- Fractional flow reserve based on computed tomography: an overview.European heart journal supplements : journal of the European Society of Cardiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Revascularization of ischemia-producing coronary lesions is widely used in the management of coronary artery disease. However, some coronary lesions appear significant on the conventional angiogram when they are truly non-flow limiting. For this reason, it is becoming increasingly important to determine the coronary physiology. Fractional flow reserve (FFR) has emerged as a useful tool to determine the lesions that require revascularization. Measurement of FFR during invasive coronary angiography now has a class IA indication from the European Society of Cardiology for identifying hemodynamically significant coronary lesions when noninvasive evidence of myocardial ischemia is unavailable. Current data on FFR can be broadly classified into studies that compare the diagnostic accuracy of FFR measurement compared with other noninvasive modalities and studies that test treatment strategies of patients with intermediate coronary stenoses using a threshold value for FFR and that have clinical outcomes as endpoints. In this review, we will discuss the concept of FFR, current evidence supporting its usage, and future perspectives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.