ArticleInternational ophthalmology2015
Therapeutic penetrating keratoplasty for infectious and non-infectious corneal ulcers.
Article in International ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Therapeutic penetrating keratoplasty for recalcitrant microbial keratitis: An update.World journal of transplantation · 2026Review
- Evaluation and comparison of the clinical significance of miR-21-5p levels from different specimen sources in patients with fungal keratitis.BMC ophthalmology · 2026Article
- Outcomes of Therapeutic and Tectonic Penetrating Keratoplasty for Advanced Corneal Disease.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Recurrence of perforation and overall patient survival after penetrating keratoplasty versus amniotic membrane transplantation in corneal perforation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Combined Photoactivated Chromophore for Infectious Keratitis-Corneal Collagen Cross-Linking (PACK-CXL) and Therapeutic Penetrating Keratoplasty for Resistant Bacterial Keratitis.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Efficacy of Lamellar Keratoplasty with Acellular Porcine Corneal Stroma in Treatment for Infectious Central and Peripheral Corneal Ulcers.Therapeutics and clinical risk management · 2021Article
- Long-term outcomes of therapeutic penetrating keratoplasty for microbial keratitis in a tertiary care center in Turkey.International ophthalmology · 2020Article
- Clinical outcome after air-assisted manual deep anterior lamellar keratoplasty for fungal keratitis poorly responsive to medical treatment.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Outcome of therapeutic penetrating keratoplasty in advanced infectious keratitis.Journal of current ophthalmology · 2018Article
- Results of therapeutic penetrating keratoplasty for bacterial and fungal keratitis.International ophthalmology · 2017Article
- Surgical management of corneal infections.Current opinion in ophthalmology · 2016Review
- Outcomes of Infectious versus Sterile Perforated Corneal Ulcers after Therapeutic Penetrating Keratoplasty in the United States.Journal of ophthalmology · 2016Article
- Review of clinical and basic approaches of fungal keratitis.International journal of ophthalmology · 2016Review
- Non-antibiotic management of bacterial keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study reports the outcomes of therapeutic penetrating keratoplasties, defined as keratoplasties performed to eradicate active infectious corneal diseases or to repair a structural defect of the cornea. The records of 24 eyes of 24 patients (17 female and 7 male) treated with therapeutic penetrating keratoplasty between 2002 and 2010 were evaluated retrospectively. Patients were divided into infectious keratitis group and non-infectious keratitis group. The mean age was 52.12 ± 17.91 years. The median follow-up time was 22 months (min-max: 6-96). Therapeutic success was achieved and eyes were preserved in 23 patients and one patient required evisceration for recurrent fungal infection. At the end of the follow-up period, 92.9 % (n = 13) and 77.8 % (n = 7) of grafts remained clear in the infectious and non-infectious groups, respectively (p = 0.538). Visual acuity (VA) improved at least one Snellen line in 23 patients. The mean postoperative decimal VA was 0.2 ± 0.3 and 0.1 ± 0.3 in the infectious and non-infectious groups, respectively (p = 0.12). Amniotic membrane transplantation was performed in two eyes preoperatively and in four eyes postoperatively. Therapeutic penetrating keratoplasty continues to be an effective method in the treatment process of serious perforated and non-perforated corneal infectious and non-infectious diseases resistant to medical and other surgical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.