ArticleEuropean journal of nuclear medicine and molecular imaging2014
Comparison of MR-based attenuation correction and CT-based attenuation correction of whole-body PET/MR imaging.
Article in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Zero-TE MRI-based attenuation correction for bone components on chest [Annals of nuclear medicine · 2026Article
- Respiratory motion-corrected quiescent period gating magnetic resonance attenuation correction (Q.MRAC) for enhancing quantitative accuracy in hepatic [18F]FDG PET/MRI: a dual-domain motion compensation study.Quantitative imaging in medicine and surgery · 2026Article
- Superiority of long axial field-of-viewEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Evidence for a role of skull bone marrow in human chronic pain as revealed by TSPO PET imaging.medRxiv : the preprint server for health sciences · 2025Article
- Prospective comparison of positron emission tomography (PET)/magnetic resonance and PET/computed tomography dosimetry in hepatic malignant neoplastic disease afterJournal of gastrointestinal oncology · 2024Article
- PET/MRI imaging in neuroendocrine neoplasm.Abdominal radiology (New York) · 2023Review
- Imaging of Angiogenesis in White Matter Hyperintensities.Journal of the American Heart Association · 2023Article
- A review of PET attenuation correction methods for PET-MR.EJNMMI physics · 2023Review
- Application of a Flexible PET Scanner Combined with 3 T MRI Using Non-local Means Reconstruction: Qualitative and Quantitative Comparison with Whole-Body PET/CT.Molecular imaging and biology · 2022Article
- Monte Carlo Characterization of the Trimage Brain PET System.Journal of imaging · 2022Article
- Comparison of Conventional and Radiomic Features betweenBiomolecules · 2021Article
- CardiovascularJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- In-vivo imaging of neuroinflammation in veterans with Gulf War illness.Brain, behavior, and immunity · 2020Article
- mDixon-Based Synthetic CT Generation for PET Attenuation Correction on Abdomen and Pelvis Jointly Using Transfer Fuzzy Clustering and Active Learning-Based Classification.IEEE transactions on medical imaging · 2020Article
- UTE-mDixon-based thorax synthetic CT generation.Medical physics · 2019Article
- Validation of MR-Based Attenuation Correction of a Newly Released Whole-Body Simultaneous PET/MR System.BioMed research international · 2019Article
- Comparison of PET/CT and PET/MR imaging and dosimetry of yttrium-90 (EJNMMI physics · 2018Article
- Quantitative myocardial blood flow imaging with integrated time-of-flight PET-MR.EJNMMI physics · 2017Article
- PET/MRI in the Presence of Metal Implants: Completion of the Attenuation Map from PET Emission Data.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2017Article
- SUV-quantification of physiological lung tissue in an integrated PET/MR-system: Impact of lung density and bone tissue.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeThe objective of this study was to evaluate the performance of the built-in MR-based attenuation correction (MRAC) included in the combined whole-body Ingenuity TF PET/MR scanner and compare it to the performance of CT-based attenuation correction (CTAC) as the gold standard.
methodsIncluded in the study were 26 patients who underwent clinical whole-body FDG PET/CT imaging and subsequently PET/MR imaging (mean delay 100 min). Patients were separated into two groups: the alpha group (14 patients) without MR coils during PET/MR imaging and the beta group (12 patients) with MR coils present (neurovascular, spine, cardiac and torso coils). All images were coregistered to the same space (PET/MR). The two PET images from PET/MR reconstructed using MRAC and CTAC were compared by voxel-based and region-based methods (with ten regions of interest, ROIs). Lesions were also compared by an experienced clinician.
resultsBody mass index and lung density showed significant differences between the alpha and beta groups. Right and left lung densities were also significantly different within each group. The percentage differences in uptake values using MRAC in relation to those using CTAC were greater in the beta group than in the alpha group (alpha group -0.2 ± 33.6%, R(2) = 0.98, p < 0.001; beta group 10.31 ± 69.86%, R(2) = 0.97, p < 0.001).
conclusionIn comparison to CTAC, MRAC led to underestimation of the PET values by less than 10% on average, although some ROIs and lesions did differ by more (including the spine, lung and heart). The beta group (imaged with coils present) showed increased overall PET quantification as well as increased variability compared to the alpha group (imaged without coils). PET data reconstructed with MRAC and CTAC showed some differences, mostly in relation to air pockets, metallic implants and attenuation differences in large bone areas (such as the pelvis and spine) due to the segmentation limitation of the MRAC method.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.