ArticlePloS one2014
Altered BOLD response during inhibitory and error processing in adolescents with anorexia nervosa.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies.Nutrients · 2019Pooled it
- A systematic review of reviews of neurocognitive functioning in eating disorders: The state-of-the-literature and future directions.The International journal of eating disorders · 2018Pooled it
- A Randomised Controlled Trial of Neuronavigated Repetitive Transcranial Magnetic Stimulation (rTMS) in Anorexia Nervosa.PloS one · 2016Trial
- Neurocognitive Profiles in Parents of Autistic Children and Parents of Children with Anorexia Nervosa.Journal of autism and developmental disorders · 2025Article
- Exploring the relationship between proactive inhibition and restrictive eating behaviours in severe and enduring anorexia nervosa (SE-AN).Journal of eating disorders · 2025Article
- Severe enduring anorexia nervosa (SE-AN) treatment options and their effectiveness: a review of literature.Journal of eating disorders · 2024Review
- Change in motivational bias during treatment predicts outcome in anorexia nervosa.The International journal of eating disorders · 2024Article
- Altered processing of conflicting body representations in women with restrictive anorexia nervosa.Psychological research · 2023Article
- Genetics and neurobiology of eating disorders.Nature neuroscience · 2022Review
- Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive-Compulsive Disorder.Frontiers in human neuroscience · 2022Review
- Attenuated neuronal and autonomic responses during error processing in anorexia nervosa.Brain and behavior · 2021Article
- Personality Traits Induce Different Brain Patterns When Processing Social and Valence Information.Frontiers in psychology · 2021Article
- Clinical and Cognitive Functioning Changes After Partial Hospitalization in Patients With Anorexia Nervosa.Frontiers in psychiatry · 2021Article
- Set-shifting in adolescents with weight-restored anorexia nervosa and their unaffected family members.Journal of psychiatric research · 2019Article
- Cognitive Neuroscience of Eating Disorders.The Psychiatric clinics of North America · 2019Review
- Anorexia Nervosa and a Lost Emotional Self: A Psychological Formulation of the Development, Maintenance, and Treatment of Anorexia Nervosa.Frontiers in psychology · 2019Article
- Attention networks in adolescent anorexia nervosa.European child & adolescent psychiatry · 2018Article
- Cortical thickness patterns as state biomarker of anorexia nervosa.The International journal of eating disorders · 2018Article
- The real-life costs of emotion regulation in anorexia nervosa: a combined ecological momentary assessment and fMRI study.Translational psychiatry · 2018Article
- Neuromodulation in eating disorders and obesity: a promising way of treatment?Neuropsychiatric disease and treatment · 2018Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIndividuals with anorexia nervosa (AN) are often cognitively rigid and behaviorally over-controlled. We previously showed that adult females recovered from AN relative to healthy comparison females had less prefrontal activation during an inhibition task, which suggested a functional brain correlate of altered inhibitory processing in individuals recovered from AN. However, the degree to which these functional brain alterations are related to disease state and whether error processing is altered in AN individuals is unknown. METHODOLOGY/PRINCIPAL
findingsIn the current study, ill adolescent AN females (n = 11) and matched healthy comparison adolescents (CA) with no history of an eating disorder (n = 12) performed a validated stop signal task (SST) during functional magnetic resonance imaging (fMRI) to explore differences in error and inhibitory processing. The groups did not differ on sociodemographic variables or on SST performance. During inhibitory processing, a significant group x difficulty (hard, easy) interaction was detected in the right dorsal anterior cingulate cortex (ACC), right middle frontal gyrus (MFG), and left posterior cingulate cortex (PCC), which was characterized by less activation in AN compared to CA participants during hard trials. During error processing, a significant group x accuracy (successful inhibit, failed inhibit) interaction in bilateral MFG and right PCC was observed, which was characterized by less activation in AN compared to CA participants during error (i.e., failed inhibit) trials. CONCLUSION/SIGNIFICANCE: Consistent with our prior findings in recovered AN, ill AN adolescents, relative to CA, showed less inhibition-related activation within the dorsal ACC, MFG and PCC as inhibitory demand increased. In addition, ill AN adolescents, relative to CA, also showed reduced activation to errors in the bilateral MFG and left PCC. These findings suggest that altered prefrontal and cingulate activation during inhibitory and error processing may represent a behavioral characteristic in AN that is independent of the state of recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.