ArticlePloS one2014
DNA loss at the Ceratocystis fimbriata mating locus results in self-sterility.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Identification, diversity analysis and control of the pathogens causing Ceratocystis wilt of Camphora officinarum in Southern China.Pest management science · 2026Article
- Mating-type locus structure affects gene expression in unidirectional mating-type switching fungi.G3 (Bethesda, Md.) · 2026Article
- A Study on the Species Diversity, Mating Types, and Clinical Relevance of Trichophyton mentagrophytes/interdigitale Complex Infections in Guizhou Province.Mycopathologia · 2026Article
- Lineage-specific diversity of pheromone response pathway genes is independent of mating strategy in Ceratocystidaceae.BMC genomics · 2026Article
- Structure of the Mating-Type Genes and Mating Systems ofJournal of fungi (Basel, Switzerland) · 2023Article
- Evidence of Biparental Mitochondrial Inheritance from Self-Fertile Crosses between Closely Related Species ofJournal of fungi (Basel, Switzerland) · 2023Article
- Article
- Needles in fungal haystacks: Discovery of a putative a-factor pheromone and a unique mating strategy in the Leotiomycetes.PloS one · 2023Article
- Truncation ofMicrobiology spectrum · 2022Article
- Comparative Genomics Reveals Evolutionary Traits, Mating Strategies, and Pathogenicity-Related Genes Variation ofFrontiers in microbiology · 2022Article
- Genetic Networks That Govern Sexual Reproduction in the Pezizomycotina.Microbiology and molecular biology reviews : MMBR · 2021Review
- Molecular Dissection of Perithecial Mating Line Development inApplied and environmental microbiology · 2021Article
- Quantification of Outcrossing Events in Haploid Fungi Using Microsatellite Markers.Journal of fungi (Basel, Switzerland) · 2020Article
- IMA Genome-F 11: Draft genome sequences ofIMA fungus · 2019Article
- NewPersoonia · 2018Article
- Ceratocystis cacaofunesta genome analysis reveals a large expansion of extracellular phosphatidylinositol-specific phospholipase-C genes (PI-PLC).BMC genomics · 2018Article
- Article
- Direct repeat-mediated DNA deletion of the mating type MAT1-2 genes results in unidirectional mating type switching in Sclerotinia trifoliorum.Scientific reports · 2016Article
- Article
- Fungal Planet description sheets: 320-370.Persoonia · 2015Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungi have evolved a remarkable diversity of reproductive strategies. Some of these, most notably those of the model fungi, have been well studied but others are poorly understood. The latter is also true for uni-directional mating type switching, which has been reported in only five fungal genera, including Ceratocystis. Mating type switching allows a self-fertile fungal isolate to produce both self-fertile and self-sterile offspring. This study considered the molecular nature of uni-directional mating type switching in the type species of Ceratocystis, C. fimbriata. To do this, the genome of C. fimbriata was first examined for the presence of mating type genes. Three mating genes (MAT1-1-1, MAT1-2-1 and MAT1-1-2) were found in an atypical organisation of the mating type locus. To study the effect that uni-directional switching has on this locus, several self-sterile offspring were analysed. Using a combination of next generation and conventional Sanger sequencing, it was shown that a 3581 base pair (bp) region had been completely deleted from the MAT locus. This deletion, which includes the entire MAT1-2-1 gene, results in the permanent loss of self-fertility, rendering these isolates exclusively self-sterile. Our data also suggest that the deletion mechanism is tightly controlled and that it always occurs at the same genomic position. Two 260 bp direct repeats flanking the deleted region are strongly implicated in the process, although the exact mechanism behind the switching remains unclear.
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