ReviewSoft matter2014
Physics of cell adhesion: some lessons from cell-mimetic systems.
Review in Soft matter, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 138 citations in OpenAlex.
- Modeling mechanochemical coupling in optogenetically activated cell layers.Biophysical journal · 2026Article
- Enhancing Bacterial Adhesion with Hydro-Softened Chitosan Films.ACS macro letters · 2025Article
- Adhesion strength, cell packing density and cell surface buckling in pericellular matrix-mediated tissue cohesion.Development (Cambridge, England) · 2025Article
- The role of elasticity on adhesion and clustering of neurons on soft surfaces.Communications biology · 2024Article
- Thermal fluctuations of the lipid membrane determine particle uptake into Giant Unilamellar Vesicles.Nature communications · 2023Article
- Observing Membrane and Cell Adhesion via Reflection Interference Contrast Microscopy.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Low Surface Potential with Glycoconjugates Determines Insect Cell Adhesion at Room Temperature.The journal of physical chemistry letters · 2022Article
- Peeling dynamics of fluid membranes bridged by molecular bonds: moving or breaking.Journal of the Royal Society, Interface · 2022Article
- Characterising the mechanics of cell-cell adhesion in plants.Quantitative plant biology · 2022Review
- Osteoblastic cell response to AlBioImpacts : BI · 2022Article
- Interplay of receptor-ligand binding and lipid domain formation during cell adhesion.Frontiers in molecular biosciences · 2022Review
- Systems for Muscle Cell Differentiation: From Bioengineering to Future Food.Micromachines · 2021Review
- Molecular Biomechanics Controls Protein Mixing and Segregation in Adherent Membranes.International journal of molecular sciences · 2021Article
- Review
- Simultaneous Determination of Human Erythrocyte Deformability and Adhesion Energy: A Novel Approach Using a Microfluidic Chamber and the "Glass Effect".Cell biochemistry and biophysics · 2021Article
- Critical role of lipid membranes in polarization and migration of cells: a biophysical view.Biophysical reviews · 2021Review
- Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion.Frontiers in molecular biosciences · 2021Article
- Mechanoregulation of PDZ Proteins, An Emerging Function.Methods in molecular biology (Clifton, N.J.) · 2021Review
- Adhesion of Epithelial Cells to PNIPAm Treated Surfaces for Temperature-Controlled Cell-Sheet Harvesting.ACS applied materials & interfaces · 2020Article
- Synergistic factors control kinase-phosphatase organization in B-cells engaged with supported bilayers.Molecular biology of the cell · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of material properties and biological functions of cells. It is controlled by competition of short range attractive forces, medium range repellant forces and the elastic stresses associated with local and global deformation of the composite cell envelopes. We review the basic physical rules governing the physics of cell adhesion learned by studying cell-mimetic systems and demonstrate the importance of these rules in the context of cellular systems. We review how adhesion induced micro-domains couple to the intracellular actin and microtubule networks allowing cells to generate strong forces with a minimum of attractive cell adhesion molecules (CAMs) and to manipulate other cells through filopodia over micrometer distances. The adhesion strength can be adapted to external force fluctuations within seconds by varying the density of attractive and repellant CAMs through exocytosis and endocytosis or protease-mediated dismantling of the CAM-cytoskeleton link. Adhesion domains form local end global biochemical reaction centres enabling the control of enzymes. Actin-microtubule crosstalk at adhesion foci facilitates the mechanical stabilization of polarized cell shapes. Axon growth in tissue is guided by attractive and repulsive clues controlled by antagonistic signalling pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.