ArticlePloS one2014
Diagnosis of Carrion's disease by direct blood PCR in thin blood smear negative samples.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Leptospira spp. and Rickettsia spp. as pathogens with zoonotic potential causing acute undifferentiated febrile illness in a central-eastern region of Peru.BMC research notes · 2024Article
- Evaluation of the available animal models forOne health (Amsterdam, Netherlands) · 2024Review
- Detection of Bartonella vinsonii, Anaplasma platys and Bartonella sp. in didelphis marsupialis, Pecari tajacu and Chelonoidis denticulate: Peru.BMC research notes · 2023Article
- Whole Genome Sequencing of Antibiotic Resistant Genes in Isolates from Surfaces in a Science Laboratory.Turkish journal of pharmaceutical sciences · 2022Article
- Immunogenic Peptides from Pap31 and SCS-α ofPathogens (Basel, Switzerland) · 2021Article
- Molecular detection and clinical characteristics of Bartonella bacilliformis, Leptospira spp., and Rickettsia spp. in the Southeastern Peruvian Amazon basin.BMC infectious diseases · 2018Article
- Molecular Detection ofThe American journal of tropical medicine and hygiene · 2018Article
- Molecular identification of Bartonella bacilliformis in ticks collected from two species of wild mammals in Madre de Dios: Peru.BMC research notes · 2018Article
- Carrion's Disease: the Sound of Silence.Clinical microbiology reviews · 2018Review
- Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru.BMC research notes · 2017Article
- Universal direct PCR amplification system: a time- and cost-effective tool for high-throughput applications.3 Biotech · 2017Article
- Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion's disease in Peru.PLoS neglected tropical diseases · 2017Article
- Infectious agents, Leptospira spp. and Bartonella spp., in blood donors from Cajamarca, Peru.Blood transfusion = Trasfusione del sangue · 2016Article
- Carrion's disease after blood transfusion.Blood transfusion = Trasfusione del sangue · 2016Article
- Review
- Succinyl-CoA Synthetase: New Antigen Candidate of Bartonella bacilliformis.PLoS neglected tropical diseases · 2016Article
- Evaluation of PCR Approaches for Detection of Bartonella bacilliformis in Blood Samples.PLoS neglected tropical diseases · 2016Article
- Multi-Locus Sequence Typing of Bartonella bacilliformis DNA Performed Directly from Blood of Patients with Oroya's Fever During a Peruvian Outbreak.PLoS neglected tropical diseases · 2016Article
- Possible vertical transmission of Bartonella bacilliformis in Peru.The American journal of tropical medicine and hygiene · 2015Article
- Rapid and sensitive detection of Bartonella bacilliformis in experimentally infected sand flies by loop-mediated isothermal amplification (LAMP) of the Pap31 gene.PLoS neglected tropical diseases · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bartonella bacilliformis is the etiologic agent of Carrion's disease. This disease has two well established phases, the most relevant being the so called Oroya Fever, in which B. bacilliformis infect the erythrocytes resulting in severe anemia and transient immunosuppression, with a high lethality in the absence of adequate antibiotic treatment. The presence of B. bacilliformis was studied in 113 blood samples suspected of Carrion's disease based on clinical criteria, despite the absence of a positive thin blood smear, by two different PCR techniques (using Bartonella-specific and universal 16S rRNA gene primers), and by bacterial culture. The specific 16S rRNA gene primers revealed the presence of 21 B. bacilliformis and 1 Bartonella elizabethae, while universal primers showed both the presence of 3 coinfections in which a concomitant pathogen was detected plus Bartonella, in addition to the presence of infections by other microorganisms such as Agrobacterium or Bacillus firmus. These data support the need to implement molecular tools to diagnose Carrion's disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.