ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2014
Risk factors for depression in patients undergoing hematopoietic cell transplantation.
Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Exposure to a patient-centered, Web-based intervention for managing cancer symptom and quality of life issues: impact on symptom distress.Journal of medical Internet research · 2015Trial
- Personal resilience resources predict post-stem cell transplant cancer survivors' psychological outcomes through reductions in depressive symptoms and meaning-making.Journal of psychosocial oncologyTrial
- Depression and anxiety in cancer patient enrolled in clinical trials with serious adverse events.Cancer medicine · 2023Article
- Psychological states and needs among post-allogeneic hematopoietic stem cell transplantation survivors.Cancer medicine · 2023Article
- Inflammatory cytokines and depression symptoms following hematopoietic cell transplantation.Brain, behavior, and immunity · 2023Article
- The Prospective Effects of Coping Strategies on Mental Health and Resilience at Five Months after HSCT.Healthcare (Basel, Switzerland) · 2023Article
- Depression and anxiety among hemophilia patients enrolled in clinical trials: a multi-center cohort study.Annals of hematology · 2023Article
- Common mental disorders in hematopoietic stem cell transplant patients: a scoping review.Revista brasileira de enfermagem · 2023Article
- A biobehavioral intervention to enhance recovery following hematopoietic cell transplantation: Protocol for a feasibility and acceptability randomized control trial.Contemporary clinical trials communications · 2022Article
- Neurocognitive Impairment After Hematopoietic Stem Cell Transplant for Hematologic Malignancies: Phenotype and Mechanisms.The oncologist · 2021Review
- Sleep Disruption, Fatigue, and Depression as Predictors of 6-Year Clinical Outcomes Following Allogeneic Hematopoietic Cell Transplantation.Journal of the National Cancer Institute · 2021Article
- Psychosocial aspects of hematopoietic stem cell transplantation.World journal of transplantation · 2021Review
- Mental health and quality of life of patients undergoing hematopoietic stem cell transplantation (HSCT) prior to hospitalization: a cross-sectional complete state health study.Health psychology and behavioral medicine · 2021Article
- Coping strategies modify risk of depression associated with hematopoietic cell transplant symptomatology.Journal of health psychology · 2018Article
- Neurocognitive dysfunction in hematopoietic cell transplant recipients: expert review from the late effects and Quality of Life Working Committee of the CIBMTR and complications and Quality of Life Working Party of the EBMT.Bone marrow transplantation · 2018Review
- Neurocognitive Dysfunction in Hematopoietic Cell Transplant Recipients: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Complications and Quality of Life Working Party of the European Society for Blood and Marrow Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2018Review
- Risk factors for depression and fatigue among survivors of hematopoietic cell transplantation.Cancer · 2016Article
- Distress prior to undergoing hematopoietic stem cell transplantation: demographic and symptom correlations and establishing a baseline.Patient related outcome measures · 2016Article
- Evaluation of Quality of Life and Care Needs of Turkish Patients Undergoing Hematopoietic Stem Cell Transplantation.Nursing research and practice · 2016Article
- Self-reported adherence to oral cancer therapy: relationships with symptom distress, depression, and personal characteristics.Patient preference and adherence · 2015Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
Despite the prevalence and known adverse impacts of depression after hematopoietic cell transplantation (HCT), little is known about the trajectory of depression occurring after HCT, or which pretransplantation risk factors might help predict new or worsening post-HCT depression. This secondary analysis evaluated the relationships between pre-HCT patient-reported outcomes and demographic characteristics and post-HCT depression. A total of 228 adult HCT patients were evaluated pre-HCT (T1) and again at 6 to 7 weeks post-HCT (T2), using touch-screen computers in the transplantation clinic during participation in a larger trial. Measures evaluated included the Symptom Distress Scale, the EORTC QLQ-C30 for quality of life, a single-item pain intensity question, and the Patient Health Questionnaire 9 for measurement of depression. At T1, rates of depression were quite low, with only 6% of participants reporting moderate or higher depression. At T2, however, the prevalence of moderate or higher depression was 31%. We observed a strong linear relationship in PHQ-9 scores between T1 and T2 (P < .0001). Depression score at T1 was a significant predictor of depression score at T2 (P = .03), as was poorer emotional function at T1 (P < .01). Our results indicate that post-HCT depression is common, even in patients with a low pre-HCT depression score. Frequent screening for symptoms of depression at critical time points, including 6 to 7 weeks post-HCT, are needed in this population, followed by referrals to supportive care as appropriate.
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