Evidence map›Paper›PMID 24648930›Full record

ArticleBiomedical reports2013

Construction and expression of a recombinant eukaryotic expression plasmid containing the

Jun-Yuan Gong, Xin Liu, Yan Dong, Tian-Hong Zhou, Jun-Wu Li

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun-Yuan GongDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, P.R. China.
Xin LiuDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, P.R. China.
Yan DongDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, P.R. China.
Tian-Hong ZhouDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, P.R. China.
Jun-Wu LiDepartment of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, P.R. China.
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 10-20% of the population remains unresponsive or weakly responsive to hepatitis B vaccine, which is composed of hepatitis B surface antigen HBsAg (S protein). Therefore, it is necessary to develop a hepatitis B vaccine with a better penetrating and responsive rate. In the present study, a plasmid pVAX1-L-GM was constructed and its immunomodulatory effect of as hepatitis B virus (HBV) DNA vaccine was analyzed through the immunization of BALB/c mice. Immune responses were measured after immunization by anti-HBsAg, proliferation of splenocytes, the number of CD4

Indexed as

granulocyte-macrophage colony stimulating factorhepatitis B viruslarge envelope proteinpreS1-preS2/S gene

Identifiers

PMID24648930
PMCPMC3956218
OpenAlexW1983894061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.