ReviewVascular health and risk management2014
Challenges associated with peripheral arterial disease in women.
Review in Vascular health and risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Diabetes as a risk factor for incident peripheral arterial disease in women compared to men: a systematic review and meta-analysis.Cardiovascular diabetology · 2020Pooled it
- Efficacy and Safety of Adjunctive Cilostazol to Clopidogrel-Treated Diabetic Patients With Symptomatic Lower Extremity Artery Disease in the Prevention of Ischemic Vascular Events.Journal of the American Heart Association · 2021Trial
- Trends in the mortality of vascular intestinal disorders in the USA: a CDC WONDER analysis.BMJ open · 2026Article
- Vascular Diseases in Women: Do Women Suffer from Them Differently?Journal of clinical medicine · 2024Review
- Lower All-Cause Mortality Risk in Females and Males with Peripheral Artery Disease following Pain-Free Home-Based Exercise: A 7-Year Observational Study.Journal of personalized medicine · 2023Article
- Use of the Walking Impairment Questionnaire and Walking Estimated-Limitation Calculated by History questionnaire to detect maximal walking distance equal to or lower than 250 m in patients with lower extremity arterial disease.Frontiers in cardiovascular medicine · 2023Article
- Article
- Risk of peripheral artery disease according to race and sex: The Atherosclerosis Risk in Communities (ARIC) study.Atherosclerosis · 2021Article
- Effects of Physical Rehabilitation on Spatiotemporal Gait Parameters and Ground Reaction Forces of Patients with Intermittent Claudication.Journal of clinical medicine · 2020Article
- Gender Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication.Journal of women's health (2002) · 2019Article
- Gender variation in symptomatic peripheral arterial occlusive disease among type-2 diabetic patients.SAGE open medicine · 2019Article
- Association of sex and height with a lower ankle brachial index in the general population.Vascular medicine (London, England) · 2018Article
- Exaggerated cardiovascular responses to treadmill running in rats with peripheral arterial insufficiency.American journal of physiology. Heart and circulatory physiology · 2018Article
- Amputation Risk in Patients with Diabetes Mellitus and Peripheral Artery Disease Using Statewide Data.Annals of vascular surgery · 2016Article
- Sex differences in the outcomes of peripheral arterial disease: a population-based cohort study.CMAJ openArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral arterial disease (PAD) is an increasingly recognized disorder that is associated with functional impairment, quality-of-life deterioration, increased risk of cardiovascular ischemic events, and increased risk of total and cardiovascular mortality. Although earlier studies suggested that PAD was more common in men, recent reports based on more sensitive tests have shown that the prevalence of PAD in women is at least the same as in men, if not higher. PAD tends to present itself asymptomatically or with atypical symptoms more frequently in women than in men, and is associated with comorbidities or situations particularly or exclusively found in the female sex, such as osteoporosis, hypothyroidism, the use of oral contraceptives, and a history of complications during pregnancy. Fat-distribution patterns and differential vascular characteristics in women may influence the interpretation of diagnostic methods, whereas sex-related vulnerability to drugs typically used in subjects with PAD, differences in risk-factor distribution among sexes, and distinct responses to revascularization procedures in men and women must be taken into account for proper disease management. All these issues pose important challenges associated with PAD in women. Of note, this group has classically been underrepresented in research studies. As a consequence, several sex-related challenges regarding diagnosis and management issues should be acknowledged, and research gaps should be addressed in order to successfully deal with this major health issue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.