Evidence map›Paper›PMID 24648061›Full record

ReviewClinical research in cardiology : official journal of the German Cardiac Society2014

Worldwide TAVI registries: what have we learned?

Stephan Haussig, Gerhard Schuler, Axel Linke

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Investigating the role of acute mental stress on endothelial dysfunction: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Pooled it
  2. Trial
  3. Large-scale experience with an anchorless vascular closure device in a real-life clinical setting.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Trial
  4. Fully automated quantification of biventricular volumes and function in cardiovascular magnetic resonance: applicability to clinical routine settings.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  5. Article
  6. Article
  7. Thrombosis of TAVI prosthesis-cause for concern or innocent bystander? A comment and review of currently available data.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Silent ischemic brain lesions after transcatheter aortic valve replacement: lesion distribution and predictors.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Article
  14. Clinical impact of a new left bundle branch block following TAVI implantation: 1-year results of the TAVIK cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Article
  15. Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2014.Clinical research in cardiology : official journal of the German Cardiac Society · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stephan HaussigDepartment of Internal Medicine/Cardiology, Heart Center, University of Leipzig, Strümpellstrasse 39, 04289, Leipzig, Germany.
Gerhard Schuler
Axel Linke
Leipzig University · DELeipzig Heart Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With a rapidly aging society, the number of patients with cardiovascular disease-in particular aortic stenosis-is progressively increasing. Although conventional aortic valve replacement remains the only treatment known to improve prognosis and symptoms in symptomatic patients with aortic stenosis, about one-third are still withhold from the life-saving therapy. Based on the compelling evidence of the randomized Placement of Aortic transcatheter valves (PARTNER) A and B cohort, TAVI is now considered standard of care for extreme risk and inoperable patients and is an alternative to surgery for high-risk patients with symptomatic aortic stenosis. However, these patients were super-selected, which does not reflect a clinical real-world situation. TAVI registries represent a real-world scenario, and therefore provide the evidence for the treatment of high-risk patients (regarding comorbidities and anatomical factors) in daily clinical life. The review will focus on the recently published Edwards SAPIEN, Medtronic CoreValve and mixed (national) registries with the focus on short- and midterm outcome. These registries suggest that the growing experience of the operators with regard to patient selection, prevention, recognition and treatment of procedural complications together with the developments in valve design will improve the short-term results of TAVI. However, randomized trials in intermediate risk patients and data on long-term valve durability are a prerequisite before indications can be expanded to younger and lower risk patient population.

Indexed as

RegistriesAge FactorsAortic Valve StenosisHeart Valve Prosthesis ImplantationHumansPatient SelectionPrognosisRisk FactorsTranscatheter Aortic Valve Replacement

Identifiers

PMID24648061
OpenAlexW2063054728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.