ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014
Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Circulating Myokine Responses to Acute Endurance Exercise and Their Role in Immunoregulation: A Systematic Review and Meta-Analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Pooled it
- Sex Matters: A Comprehensive Comparison of Female and Male Hearts.Frontiers in physiology · 2022Pooled it
- Determinants of Bone Mineral Density in Postmenopausal Women: The Role of Lean and Fat Mass by Dual Energy X-Ray Absorptiometry Assessment.Journal of bone metabolism · 2025Article
- The association between glycemic indicators and bone mineral density and osteoporosis: a cross-sectional study.Scientific reports · 2025Article
- Assessment of fracture risk in diabetic patients.Journal of diabetes and metabolic disorders · 2024Review
- Physical fitness components are bone mineral density predictors in adulthood: cross-sectional study.BMC musculoskeletal disorders · 2024Article
- Bone health and body composition in transgender adults before gender-affirming hormonal therapy: data from the COMET study.Journal of endocrinological investigation · 2024Article
- Relationships between longitudinal changes in body composition and bone mineral density in middle-to-older aged Australians.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- The association between lumbar paraspinal muscle functional cross-sectional area on MRI and regional volumetric bone mineral density measured by quantitative computed tomography.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Physical activity estimated by osteogenic potential and energy expenditure has differing associations with bone mass in young adults: the raine study.Archives of osteoporosis · 2022Article
- Prospective Associations of Sugar-Sweetened Beverage Consumption During Adolescence with Body Composition and Bone Mass at Early Adulthood.The Journal of nutrition · 2022Article
- Lean Mass is Associated with, but Does Not Mediate Sex Differences in Pressure Pain Sensitivity in Healthy Adults.Journal of pain research · 2022Article
- Article
- A longitudinal comparison of appendicular bone growth and markers of strength through adolescence in a South African cohort using radiogrammetry and pQCT.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- The effect of visceral fat on the hemodilution effect of serum carcinoembryonic antigen in Korean population.PloS one · 2019Article
- Interactions between Sedentary and Physical Activity Patterns, Lean Mass, and Bone Density in Arab Men.Disease markers · 2019Article
- Relationships between muscle mass, strength and regional bone mineral density in young men.PloS one · 2019Article
- Lean mass mediates the relation between temporal summation of pain and sex in young healthy adults.Biology of sex differences · 2018Article
- Are there effects of age, gender, height, and body fat on the functional muscle-bone unit in children and adults?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Physical Activity, Physical Fitness, Body Composition, and Nutrition Are Associated with Bone Status in University Students.Nutrients · 2018Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
unlabelledThe relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass was a positive predictor of total body bone mass in females, with weaker association in males.
introductionBody weight and lean body mass are established as major determinants of bone mass, but the relationships between fat mass (including visceral fat) and peak bone mass in young adults are unclear. The aim of this study was to evaluate the associations between bone mass in young adults and three body composition measurements: lean body mass, fat mass and trunk-to-limb fat mass ratio (a surrogate measure of visceral fat).
methodsStudy participants were 574 women and 609 men aged 19-22 years from the Raine study. Body composition, total body bone mineral content (TBBMC), bone area and areal bone mineral density (TBBMD) were measured using DXA.
resultsIn multivariate linear regression models with height, lean body mass, fat mass and trunk-to-limb fat mass ratio as predictor variables, lean mass was uniquely associated with the largest proportion of variance of TBBMC and TBBMD in males (semi-partial R(2) 0.275 and 0.345, respectively) and TBBMC in females (semi-partial R(2) 0.183). Fat mass was a more important predictor of TBBMC and TBBMD in females (semi-partial R(2) 0.126 and 0.039, respectively) than males (semi-partial R(2) 0.006 and 0.018, respectively). Trunk-to-limb fat mass ratio had a weak, negative association with TBBMC and bone area in both genders (semi-partial R(2) 0.004 to 0.034).
conclusionsLean body mass has strong positive relationship with total body bone mass in both genders. Fat mass may play a positive role in peak bone mass attainment in women but the association was weaker in men; different fat compartments may have different effects.
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