Trial reportIntensive care medicine2014
Low-dose chest computed tomography for quantitative and visual anatomical analysis in patients with acute respiratory distress syndrome.
Trial report in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Characterizing heterogeneity and subphenotyping acute respiratory distress syndrome with computed tomography.Intensive care medicine experimental · 2026Review
- Effect of prone positioning on gas exchange according to lung morphology in patients with acute respiratory distress syndrome.Acute and critical care · 2022Article
- Thoracic Computed Tomography to Assess ARDS and COVID-19 Lungs.Frontiers in physiology · 2022Review
- A patient-specific approach for quantitative and automatic analysis of computed tomography images in lung disease: Application to COVID-19 patients.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021Article
- Missed or delayed diagnosis of ARDS: a common and serious problem.Intensive care medicine · 2020Review
- Imaging the Injured Lung: Mechanisms of Action and Clinical Use.Anesthesiology · 2019Review
- Lung recruitment: What has computed tomography taught us in the last decade?Annals of intensive care · 2019Article
- Magnetic Resonance Imaging for Quantitative Assessment of Lung Aeration: A Pilot Translational Study.Frontiers in physiology · 2018Article
- Ultra-low-dose sequential computed tomography for quantitative lung aeration assessment-a translational study.Intensive care medicine experimental · 2017Article
- Intensive Care Medicine in 2050: the future of medical imaging.Intensive care medicine · 2017Article
- Definition and epidemiology of acute respiratory distress syndrome.Annals of translational medicine · 2017Review
- Lung imaging: how to get better look inside the lung.Annals of translational medicine · 2017Review
- Current Concepts of ARDS: A Narrative Review.International journal of molecular sciences · 2016Review
- Opportunistic Breast Density Assessment in Women Receiving Low-dose Chest Computed Tomography Screening.Academic radiology · 2016Article
- Severe hypoxemia: which strategy to choose.Critical care (London, England) · 2016Review
- Diagnostic workup for ARDS patients.Intensive care medicine · 2016Review
- Patterns of recruitment and injury in a heterogeneous airway network model.Journal of the Royal Society, Interface · 2015Article
- Validation of computed tomography for measuring lung weight.Intensive care medicine experimental · 2014Article
- Year in review 2013: Critical Care--respirology.Critical care (London, England) · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeChest computed tomography (CT) is a fundamental tool for the characterization of acute respiratory distress syndrome (ARDS). Its frequent use is, however, hindered by the associated radiation exposure. The aim of the present study was to evaluate, in patients with ARDS, the accuracy of quantitative and visual anatomical lung analysis performed on low-dose CT. We hypothesized that low-dose CT would provide accurate quantitative and visual anatomical results.
methodsChest CT was performed in 45 ARDS patients in static conditions at set airway pressures of 45 and 15 or 45 and 5 cmH2O. During each pause, two consecutive scans were obtained at two different tube current-time products (mAs). In 24 patients 110 mAs was coupled with 60 mAs; in 21 patients 110 was coupled with 30 mAs. All other CT parameters were kept unaltered. Quantitative and visual anatomical results obtained at different mAs were compared via Bland-Altman analysis.
resultsGood agreements were observed between 110 and 60 mAs and between 110 and 30 mAs both for quantitative and visual anatomical results (all biases below 1.5%). Estimated mean effective dose at 110, 60, and 30 mAs corresponded to 5.3 ± 1.6, 2.8 ± 0.8, and 1.4 ± 0.3 mSv, respectively.
conclusionsIn patients with ARDS a reduction of mAs up to 30 (70 % effective dose reduction) can be achieved without significant effect on quantitative and visual anatomical results. Low-dose chest CT, with related quantitative and visual anatomical analysis, could be a valuable tool to characterize and potentially monitor lung disease in patients with ARDS.
Indexed as
Identifiers
24647812What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.