ArticlePloS one2014
openSNP--a crowdsourced web resource for personal genomics.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.
- Mapping of Crowdsourcing in Health: Systematic Review.Journal of medical Internet research · 2018Pooled it
- Bridging genomics' greatest challenge: The diversity gap.Cell genomics · 2025Review
- Privacy-Preserving Collaborative Population Stratification with Dynamic Algorithm and Hyperparameter Selection.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2025Article
- Assessing Privacy Vulnerabilities in Genetic Data Sets: Scoping Review.JMIR bioinformatics and biotechnology · 2024Article
- Exploring the use of Artificial Genomes for Genome-wide Association Studies through the lens of Utility and Privacy.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
- Privacy-preserving federated genome-wide association studies via dynamic sampling.Bioinformatics (Oxford, England) · 2023Article
- Automated machine learning for genome wide association studies.Bioinformatics (Oxford, England) · 2023Article
- Enabling tradeoffs in privacy and utility in genomic data Beacons and summary statistics.Genome research · 2023Article
- Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities.BMC medical genomics · 2023Article
- Hypothesis-free phenotype prediction within a genetics-first framework.Nature communications · 2023Article
- Efficient Federated Kinship Relationship Identification.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023Article
- PAGEANT: personal access to genome and analysis of natural traits.Nucleic acids research · 2022Article
- PSORS1 Locus Genotyping Profile in Psoriasis: A Pilot Case-Control Study.Diagnostics (Basel, Switzerland) · 2022Article
- An Ethics Framework for Evaluating Ownership Practices in Biomedical Citizen Science.Citizen science : theory and practice · 2022Article
- Polygenic risk scores: An overview from bench to bedside for personalised medicine.Frontiers in genetics · 2022Review
- A Sequence Obfuscation Method for Protecting Personal Genomic Privacy.Frontiers in genetics · 2022Article
- Using game theory to thwart multistage privacy intrusions when sharing data.Science advances · 2021Article
- Re-identification of individuals in genomic datasets using public face images.Science advances · 2021Article
- Linking clinotypes to phenotypes and genotypes from laboratory test results in comprehensive physical exams.BMC medical informatics and decision making · 2021Article
- Genome Reconstruction Attacks Against Genomic Data-Sharing Beacons.Proceedings on Privacy Enhancing Technologies. Privacy Enhancing Technologies Symposium · 2021Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genome-Wide Association Studies are widely used to correlate phenotypic traits with genetic variants. These studies usually compare the genetic variation between two groups to single out certain Single Nucleotide Polymorphisms (SNPs) that are linked to a phenotypic variation in one of the groups. However, it is necessary to have a large enough sample size to find statistically significant correlations. Direct-To-Consumer (DTC) genetic testing can supply additional data: DTC-companies offer the analysis of a large amount of SNPs for an individual at low cost without the need to consult a physician or geneticist. Over 100,000 people have already been genotyped through Direct-To-Consumer genetic testing companies. However, this data is not public for a variety of reasons and thus cannot be used in research. It seems reasonable to create a central open data repository for such data. Here we present the web platform openSNP, an open database which allows participants of Direct-To-Consumer genetic testing to publish their genetic data at no cost along with phenotypic information. Through this crowdsourced effort of collecting genetic and phenotypic information, openSNP has become a resource for a wide area of studies, including Genome-Wide Association Studies. openSNP is hosted at http://www.opensnp.org, and the code is released under MIT-license at http://github.com/gedankenstuecke/snpr.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.