Evidence map›Paper›PMID 24646947›Full record

ReviewCurrent opinion in rheumatology2014

Is pregnancy a risk factor for rheumatic autoimmune diseases?

Wendy Marder, Emily C Somers

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Effect of pregnancy on scleroderma progression.Journal of scleroderma and related disorders · 2023
    Article
  3. Article
  4. Article
  5. Pregnancy and autoimmune connective tissue diseases.Best practice & research. Clinical rheumatology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Wendy MarderaDivision of Rheumatology, Department of Internal Medicine bDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, University of Michigan cDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Emily C Somers
Center for Rheumatology · USUniversity of Michigan–Ann Arbor · US

Funding

Michigan BIRCWH Career Development ProgramK12HD001438 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSON, TIMOTHY RB · 2000 to 2014
$6.7M
Immune dysfunction associated with early life heavy metal exposureK01ES019909 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SOMERS, EMILY CATHERINE · 2011 to 2015
$670k
NICHD NIH HHS K12 HD001438NICHD NIH HHS K12HD001438NIEHS NIH HHS K01 ES019909NIEHS NIH HHS K01ES019909
6 · The paper itself

Abstract

purpose of reviewTo review the association of pregnancy with the risk of subsequent development of rheumatic autoimmune diseases in women, including rheumatoid arthritis (RA), systemic lupus erythematosus, and scleroderma. RECENT

findingsThere is a small but growing literature related to the risk of autoimmune rheumatic disease in association with pregnancy history. However, results conflict both in terms of the direction and magnitude of risk of disease in relationship to prior pregnancy history. Although anecdotal evidence tends to favor the premise that pregnancy is protective against certain diseases, such as RA, the heterogeneity of results precludes the ability to confirm an association in either direction. There is indication that time elapsed since pregnancy may influence risk, with the postpartum year being of particular relevance. SUMMARY: To date, a clear pattern has not emerged regarding pregnancy and the future risk of autoimmune rheumatic diseases. This topic requires greater study, and given the strong female preponderance of these diseases, future research efforts should seek to resolve this important issue.

Indexed as

Arthritis, RheumatoidAutoimmune DiseasesAutoimmunityFemaleHumansLupus Erythematosus, SystemicPregnancyPregnancy ComplicationsRheumatic DiseasesRisk FactorsScleroderma, Systemic

Identifiers

PMID24646947
PMCPMC4151322
OpenAlexW1999666635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.