ArticleThe Journal of investigative dermatology2014
Hiding in plain sight: molecular genetics applied to giant congenital melanocytic nevi.
Article in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Neurological signs, symptoms and MRI abnormalities in patients with congenital melanocytic naevi and evaluation of routine MRI-screening: systematic review and meta-analysis.Orphanet journal of rare diseases · 2022Pooled it
- Mitotic Proliferative Nodule Within a Giant Congenital Nevus: One Case Report and Updated Review.Dermatopathology (Basel, Switzerland) · 2026Review
- Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report.Oncology letters · 2025Article
- Reverse repurposing: Potential utility of cancer drugs in nonmalignant illnesses.Med (New York, N.Y.) · 2024Review
- Giant cerebriform melanocytic nevus of the scalp: A case report.Clinical case reports · 2021Article
- Oncogenic codon 13 NRAS mutation in a primary mesenchymal brain neoplasm and nevus of a child with neurocutaneous melanosis.Acta neuropathologica communications · 2014Article
- Giant Congenital Melanocytic Nevi: An Update and Emerging Therapies.Case reports in dermatologyArticle
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large and giant congenital melanocytic nevi are rare malformations that offer surprising insight into prenatal and postnatal acquisition of nevi of any size, central and peripheral nervous system development, and melanomagenesis. In this issue, Charbel et al. demonstrate the use of highly sensitive detection techniques for recurrent but difficult-to-detect mutations in NRAS and BRAF. It is now possible to systematically add a molecular qualifier to distinguish lesions that had once been considered to be equivalent based on the single visual parameter of size. These findings help to elucidate the pathophysiology of congenital melanocytic nevi and their predisposition to malignancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.